Difference between revisions of "Sandbox"

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* '''Description:''' cell-division initiation protein (septum formation), component of septosome (with [[DivIB]]) <br/><br/>
+
* '''Description:''' protein serine phosphatase, septum-associated PP2C, dephosphorylation of [[SpoIIAA]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''divIC''
+
|''spoIIE''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoIIH, spoIIK ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || cell-division protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || protein serine phosphatase, septum-associated PP2C
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || septum formation
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity
 +
required for normal formation of the asymmetric septum
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.968  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 91 kDa, 6.137  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 375 bp, 125 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2481 bp, 827 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yabQ]]'', ''[[yabR]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnSL-Glu1]]'', ''[[yabS]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11838&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11840&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:divIC_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIE_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
 
  
 
=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yabMNOPQ-divIC-yabR.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIE.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10125]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10127]
  
 
=== Additional information===
 
=== Additional information===
Line 54: Line 53:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' dephosphorylation of [[SpoIIAA]]
  
* '''Protein family:'''
+
* '''Protein family:''' PP2C phosphatase
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
Line 72: Line 71:
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[DivIC]]-[[FtsL]],  membrane bound [http://www.ncbi.nlm.nih.gov/sites/entrez/9426141 PubMed]
+
* '''Interactions:''' [[SpoIIQ]]-[[SpoIIE]]
  
 
* '''Localization:'''
 
* '''Localization:'''
Line 82: Line 81:
 
* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00620]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00640]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 115: Line 114:
  
 
=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 +
 +
[[Imrich Barak]], Slovak Academy of Science, Bratislava, Slovakia [http://imb.savba.sk/~barak/ homepage]
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 13:10, 28 April 2009

  • Description: protein serine phosphatase, septum-associated PP2C, dephosphorylation of SpoIIAA

Gene name spoIIE
Synonyms spoIIH, spoIIK
Essential no
Product protein serine phosphatase, septum-associated PP2C
Function control of SigF activity

required for normal formation of the asymmetric septum

MW, pI 91 kDa, 6.137
Gene length, protein length 2481 bp, 827 aa
Immediate neighbours trnSL-Glu1, yabS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
  • Protein family: PP2C phosphatase
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed