Difference between revisions of "Sandbox"

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* '''Description:''' methylphosphotriester-DNA alkyltransferase/ transcriptional activator of the ''[[adaA]]-[[adaB]]'' operon <br/><br/>
+
* '''Description:''' O6-methylguanine-DNA methyltransferase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''adaA''
+
|''adaB''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || methylphosphotriester-DNA alkyltransferase/ transcriptional activator of the adaAB operon
+
|style="background:#ABCDEF;" align="center"| '''Product''' || O6-methylguanine-DNA methyltransferase
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || adaptive response to alkylative DNA damage
 
|style="background:#ABCDEF;" align="center"|'''Function''' || adaptive response to alkylative DNA damage
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 9.185  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 6.152  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 633 bp, 211 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 537 bp, 179 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[alkA]]'', ''[[adaB]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[adaA]]'', ''[[ndhF]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11957&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11958&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:adaA_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:adaB_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/adaAB.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/adaAB.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10166]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10167]
  
 
=== Additional information===
 
=== Additional information===
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* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU01810]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU01820]
  
* '''E.C. number:'''
+
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.1.1.63 2.1.1.63]
  
 
=== Additional information===
 
=== Additional information===

Revision as of 17:37, 21 April 2009

  • Description: O6-methylguanine-DNA methyltransferase

Gene name adaB
Synonyms
Essential no
Product O6-methylguanine-DNA methyltransferase
Function adaptive response to alkylative DNA damage
MW, pI 19 kDa, 6.152
Gene length, protein length 537 bp, 179 aa
Immediate neighbours adaA, ndhF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AdaB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed