Difference between revisions of "Sandbox"

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* '''Description:''' zinc transporter<br/><br/>
+
* '''Description:''' thiol-disulfide oxidoreductase, with thioredoxin-like domain, required for the synthesis of the endospore peptidoglycan cortex <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''zosA''
+
|''stoA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ykvW''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoIVH, ykvV''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || P-type zinc-transporting ATPase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || thiol-disulfide oxidoreductase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || zinc uptake
+
|style="background:#ABCDEF;" align="center"|'''Function''' || spore cortex formation
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 68 kDa, 4.934  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 5.297  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1911 bp, 637 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 495 bp, 165 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[stoA]]'', ''[[ykvY]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykvU]]'', ''[[zosA]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ykvW_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:ykvV_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 41: Line 41:
 
=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' no entry
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ykvUV.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13325]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13324]
  
 
=== Additional information===
 
=== Additional information===
Line 52: Line 52:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' P-type zinc-transporting ATPase [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
* '''Catalyzed reaction/ biological activity:'''  
  
 
* '''Protein family:'''
 
* '''Protein family:'''
Line 80: Line 80:
 
* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU13850]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU13840]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 88: Line 88:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''zosA'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
* '''Operon:'''  
  
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
* '''[[Sigma factor]]:'''  
  
* '''Regulation:''' induced by hydrogen peroxide ([[PerR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
* '''Regulation:'''  
  
* '''Regulatory mechanism:''' [[PerR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''
+
* '''Additional information:'''  
  
 
=Biological materials =
 
=Biological materials =
Line 118: Line 118:
 
=References=
 
=References=
  
# Gaballa, A.and Helmann, J. D. (2002) A peroxide-induced zinc uptake system plays an important role in protection against oxidative stress in ''Bacillus subtilis''. ''Mol. Microbiol.'' '''45:''' 997-1005. [http://www.ncbi.nlm.nih.gov/sites/entrez/12180919 PubMed]
+
# Crow A, Liu Y, Carlsson Moller M, Le Brun NE, Hederstedt L. (2009) Structure and functional properties of Bacillus subtilis endospore-biogenesis factor StoA. ''J Biol Chem.'' '''Jan 13. [Epub ahead of print]''' [http://www.ncbi.nlm.nih.gov/sites/entrez/19144642  PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 20:07, 15 April 2009

  • Description: thiol-disulfide oxidoreductase, with thioredoxin-like domain, required for the synthesis of the endospore peptidoglycan cortex

Gene name stoA
Synonyms spoIVH, ykvV
Essential no
Product thiol-disulfide oxidoreductase
Function spore cortex formation
MW, pI 18 kDa, 5.297
Gene length, protein length 495 bp, 165 aa
Immediate neighbours ykvU, zosA
Hier soll was neues rein
Genetic context
YkvV context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Crow A, Liu Y, Carlsson Moller M, Le Brun NE, Hederstedt L. (2009) Structure and functional properties of Bacillus subtilis endospore-biogenesis factor StoA. J Biol Chem. Jan 13. [Epub ahead of print] PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed