Difference between revisions of "Sandbox"
| Line 1: | Line 1: | ||
| − | * '''Description:''' multidrug- | + | * '''Description:''' transcription repressor of the multidrug-resistance ''mdtRP'' operon <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''mdtR'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yusO'' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor (MarR family) |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the multidrug-resistance ''[[mdtR]]-[[mdtP]]'' operon |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || | + | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.376 |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || | + | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 465 bp, 155 aa |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yusN]]'', ''[[yusP]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | ||
|- | |- | ||
| − | |colspan="2" | '''Genetic context''' <br/> [[Image: | + | |colspan="2" | '''Genetic context''' <br/> [[Image:yusO_context.gif]] |
|- | |- | ||
|} | |} | ||
| Line 42: | Line 42: | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+ | + | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14027] |
=== Additional information=== | === Additional information=== | ||
| Line 71: | Line 71: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' | + | * '''Localization:''' |
=== Database entries === | === Database entries === | ||
| Line 93: | Line 93: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | * '''Regulatory mechanism:''' repression by | + | * '''Regulatory mechanism:''' repression by MdtR [http://www.ncbi.nlm.nih.gov/sites/entrez/19286808 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 99: | Line 99: | ||
=Biological materials = | =Biological materials = | ||
| − | * '''Mutant:''' | + | * '''Mutant:''' GP1115 (spc), available in [[Stülke]] lab |
* '''Expression vector:''' | * '''Expression vector:''' | ||
| Line 117: | Line 117: | ||
=References= | =References= | ||
| − | |||
# Kim JY, Inaoka T, Hirooka K, Matsuoka H, Murata M, Ohki R, Adachi Y, Fujita Y, Ochi K (2009) Identification and characterization of a novel multidrug resistance operon ''mdtRP'' (''yusOP'') of ''Bacillus subtilis''. ''J. Bacteriol'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/19286808 PubMed] | # Kim JY, Inaoka T, Hirooka K, Matsuoka H, Murata M, Ohki R, Adachi Y, Fujita Y, Ochi K (2009) Identification and characterization of a novel multidrug resistance operon ''mdtRP'' (''yusOP'') of ''Bacillus subtilis''. ''J. Bacteriol'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/19286808 PubMed] | ||
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | ||
Revision as of 17:52, 15 April 2009
- Description: transcription repressor of the multidrug-resistance mdtRP operon
| Gene name | mdtR |
| Synonyms | yusO |
| Essential | no |
| Product | transcription repressor (MarR family) |
| Function | regulation of the multidrug-resistance mdtR-mdtP operon |
| MW, pI | 17 kDa, 6.376 |
| Gene length, protein length | 465 bp, 155 aa |
| Immediate neighbours | yusN, yusP |
| Hier soll was neues rein | |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism: repression by MdtR PubMed
- Additional information:
Biological materials
- Mutant: GP1115 (spc), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Kim JY, Inaoka T, Hirooka K, Matsuoka H, Murata M, Ohki R, Adachi Y, Fujita Y, Ochi K (2009) Identification and characterization of a novel multidrug resistance operon mdtRP (yusOP) of Bacillus subtilis. J. Bacteriol volume: page-page. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
