MaeN

• Description: Na+/malate symporter
  
  

Gene name	maeN
Synonyms	yufR
Essential	no
Product	Na+/malate symporter
Function	malate uptake
MW, pI	47 kDa, 8.411
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	yufQ, yufS
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: 2-hydroxycarboxylate transporter family

• Paralogous protein(s): CimH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: induced by malate (MalR)

• Regulatory mechanism: MalR: transcription activation

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Tanaka, K., K. Kobayashi, and N. Ogasawara. 2003. The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Microbiology 149: 2317-2329. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed