Difference between revisions of "Stusti 2018"

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== Ribozymes (catalytically active RNAs)==
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== Ribozymes (catalytically active RNAs)(Intro)==
 
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=== The Ribosome - the role and function of ribosomal RNAs    and the central dogma of molecular biology ===
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== The Ribosome - the role and function of ribosomal RNAs    and the central dogma of molecular biology ==
 
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=== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ===
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== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
 
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=== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme and Co. ===
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== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
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<pubmed> 22454536,14730013 10554775 21930585 6297745</pubmed>
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== RNA-based second messengers ==
 
== RNA-based second messengers ==
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== Riboregulation and virulence, targeting by antibiotics ==
 
== Riboregulation and virulence, targeting by antibiotics ==
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== RNAs as essential co-factors in protein enzymes ==
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== RNA dependent DNA Polymerases - from telomerase to retroviruses==
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=== RNA dependent DNA Polymerases - from telomerase to retroviruses===
 
 
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=== RNA dependent RNA Polymerases – the RNA replicase ===
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== RNA dependent RNA Polymerases – the RNA replicase ==
 
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=== CRISPR/Cas: Science – the bacterial “immune” system ===
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== CRISPR/Cas: Science – the bacterial “immune” system ==
 
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=== CRISPR/Cas: Application and groundbreaking  perspectives ===
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== CRISPR/Cas: Application and groundbreaking  perspectives ==
 
<pubmed>    26771484 </pubmed>  
 
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=== The mysterious function and role of 6S-RNA and pRNA in bacteria ===
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== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
 
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Revision as of 13:33, 22 June 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs)(Intro)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co


RNA-based second messengers


Riboregulation and virulence, targeting by antibiotics


Riboswitches

Stefan Schwenk, Alexandra Moores, Irene Nobeli, Timothy D McHugh, Kristine B Arnvig
Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis.
Nucleic Acids Res: 2018, 46(11);5837-5849
[PubMed:29618088] [WorldCat.org] [DOI] (I p)

Laurène Bastet, Pierre Turcotte, Joseph T Wade, Daniel A Lafontaine
Maestro of regulation: Riboswitches orchestrate gene expression at the levels of translation, transcription and mRNA decay.
RNA Biol: 2018, 15(6);679-682
[PubMed:29537923] [WorldCat.org] [DOI] (I p)

Marc Vogel, Julia E Weigand, Britta Kluge, Manuel Grez, Beatrix Suess
A small, portable RNA device for the control of exon skipping in mammalian cells.
Nucleic Acids Res: 2018, 46(8);e48
[PubMed:29420816] [WorldCat.org] [DOI] (I p)

Etienne B Greenlee, Shira Stav, Ruben M Atilho, Kenneth I Brewer, Kimberly A Harris, Sarah N Malkowski, Gayan Mirihana Arachchilage, Kevin R Perkins, Madeline E Sherlock, Ronald R Breaker
Challenges of ligand identification for the second wave of orphan riboswitch candidates.
RNA Biol: 2018, 15(3);377-390
[PubMed:29135333] [WorldCat.org] [DOI] (I p)

James W Nelson, Ronald R Breaker
The lost language of the RNA World.
Sci Signal: 2017, 10(483);
[PubMed:28611182] [WorldCat.org] [DOI] (I e)

Hannah Steinert, Florian Sochor, Anna Wacker, Janina Buck, Christina Helmling, Fabian Hiller, Sara Keyhani, Jonas Noeske, Steffen Grimm, Martin M Rudolph, Heiko Keller, Rachel Anne Mooney, Robert Landick, Beatrix Suess, Boris Fürtig, Jens Wöhnert, Harald Schwalbe
Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation.
Elife: 2017, 6;
[PubMed:28541183] [WorldCat.org] [DOI] (I e)

Joseph E Wedekind, Debapratim Dutta, Ivan A Belashov, Jermaine L Jenkins
Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes.
J Biol Chem: 2017, 292(23);9441-9450
[PubMed:28455443] [WorldCat.org] [DOI] (I p)

Phillip J McCown, Keith A Corbino, Shira Stav, Madeline E Sherlock, Ronald R Breaker
Riboswitch diversity and distribution.
RNA: 2017, 23(7);995-1011
[PubMed:28396576] [WorldCat.org] [DOI] (I p)

Christopher P Jones, Adrian R Ferré-D'Amaré
Long-Range Interactions in Riboswitch Control of Gene Expression.
Annu Rev Biophys: 2017, 46;455-481
[PubMed:28375729] [WorldCat.org] [DOI] (I p)

Maja Etzel, Mario Mörl
Synthetic Riboswitches: From Plug and Pray toward Plug and Play.
Biochemistry: 2017, 56(9);1181-1198
[PubMed:28206750] [WorldCat.org] [DOI] (I p)

Svetlana V Harbaugh, Michael S Goodson, Kateri Dillon, Sarah Zabarnick, Nancy Kelley-Loughnane
Riboswitch-Based Reversible Dual Color Sensor.
ACS Synth Biol: 2017, 6(5);766-781
[PubMed:28121427] [WorldCat.org] [DOI] (I p)

Kyle E Watters, Eric J Strobel, Angela M Yu, John T Lis, Julius B Lucks
Cotranscriptional folding of a riboswitch at nucleotide resolution.
Nat Struct Mol Biol: 2016, 23(12);1124-1131
[PubMed:27798597] [WorldCat.org] [DOI] (I p)

Anna V Sherwood, Tina M Henkin
Riboswitch-Mediated Gene Regulation: Novel RNA Architectures Dictate Gene Expression Responses.
Annu Rev Microbiol: 2016, 70;361-74
[PubMed:27607554] [WorldCat.org] [DOI] (I p)

Aiming Ren, Yi Xue, Alla Peselis, Alexander Serganov, Hashim M Al-Hashimi, Dinshaw J Patel
Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep: 2015, 13(9);1800-13
[PubMed:26655897] [WorldCat.org] [DOI] (I p)

Danielle Biscaro Pedrolli, Christian Kühm, Daniel C Sévin, Michael P Vockenhuber, Uwe Sauer, Beatrix Suess, Matthias Mack
A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2015, 112(45);14054-9
[PubMed:26494285] [WorldCat.org] [DOI] (I p)

Aiming Ren, Kanagalaghatta R Rajashankar, Dinshaw J Patel
Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism.
Structure: 2015, 23(8);1375-1381
[PubMed:26118534] [WorldCat.org] [DOI] (I p)

Mingxu You, Jacob L Litke, Samie R Jaffrey
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch.
Proc Natl Acad Sci U S A: 2015, 112(21);E2756-65
[PubMed:25964329] [WorldCat.org] [DOI] (I p)

James W Nelson, Narasimhan Sudarsan, Grace E Phillips, Shira Stav, Christina E Lünse, Phillip J McCown, Ronald R Breaker
Control of bacterial exoelectrogenesis by c-AMP-GMP.
Proc Natl Acad Sci U S A: 2015, 112(17);5389-94
[PubMed:25848023] [WorldCat.org] [DOI] (I p)

Michael Dambach, Melissa Sandoval, Taylor B Updegrove, Vivek Anantharaman, L Aravind, Lauren S Waters, Gisela Storz
The ubiquitous yybP-ykoY riboswitch is a manganese-responsive regulatory element.
Mol Cell: 2015, 57(6);1099-1109
[PubMed:25794618] [WorldCat.org] [DOI] (I p)

Kazuhiro Furukawa, Arati Ramesh, Zhiyuan Zhou, Zasha Weinberg, Tenaya Vallery, Wade C Winkler, Ronald R Breaker
Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters.
Mol Cell: 2015, 57(6);1088-1098
[PubMed:25794617] [WorldCat.org] [DOI] (I p)

José A L da Silva
From the RNA world to the RNA/protein world: contribution of some riboswitch-binding species?
J Theor Biol: 2015, 370;197-201
[PubMed:25571850] [WorldCat.org] [DOI] (I p)

Arati Ramesh, Wade C Winkler
Metabolite-binding ribozymes.
Biochim Biophys Acta: 2014, 1839(10);989-994
[PubMed:24769284] [WorldCat.org] [DOI] (P p)


Protein- or tRNA-controlled RNA switches


RNA thermometers


The RNA world and evolution


RNA modification


RNA degradation/processing


Regulation by non-coding RNA


RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways

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