Revision as of 13:33, 22 June 2018

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA

RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair

Ribozymes (catalytically active RNAs)(Intro)

The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology

The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity

Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co

RNA-based second messengers

Riboregulation and virulence, targeting by antibiotics

Riboswitches

Protein- or tRNA-controlled RNA switches

RNA thermometers

The RNA world and evolution

RNA modification

RNA degradation/processing

Regulation by non-coding RNA

Yvonne Göpel, Muna A Khan, Boris Görke
Ménage à trois: post-transcriptional control of the key enzyme for cell envelope synthesis by a base-pairing small RNA, an RNase adaptor protein, and a small RNA mimic.
RNA Biol: 2014, 11(5);433-42
[PubMed:24667238] [WorldCat.org] [DOI] (I p)

Boris Görke, Jörg Vogel
Noncoding RNA control of the making and breaking of sugars.
Genes Dev: 2008, 22(21);2914-25
[PubMed:18981470] [WorldCat.org] [DOI] (P p)

RNA dependent DNA Polymerases - from telomerase to retroviruses

RNA dependent RNA Polymerases – the RNA replicase

CRISPR/Cas: Science – the bacterial “immune” system

Yoshizumi Ishino, Mart Krupovic, Patrick Forterre
History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology.
J Bacteriol: 2018, 200(7);
[PubMed:29358495] [WorldCat.org] [DOI] (I e)

Lina M Leon, Senén D Mendoza, Joseph Bondy-Denomy
How bacteria control the CRISPR-Cas arsenal.
Curr Opin Microbiol: 2018, 42;87-95
[PubMed:29169146] [WorldCat.org] [DOI] (I p)

Fuguo Jiang, Jennifer A Doudna
CRISPR-Cas9 Structures and Mechanisms.
Annu Rev Biophys: 2017, 46;505-529
[PubMed:28375731] [WorldCat.org] [DOI] (I p)

CRISPR/Cas: Application and groundbreaking perspectives

The mysterious function and role of 6S-RNA and pRNA in bacteria

Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer

Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)

Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways

Sujin Jeong, Seung Ryul Han, Young Ju Lee, Seong-Wook Lee
Selection of RNA aptamers specific to active prostate-specific antigen.
Biotechnol Lett: 2010, 32(3);379-85
[PubMed:19943183] [WorldCat.org] [DOI] (I p)

Regina Stoltenburg, Christine Reinemann, Beate Strehlitz
SELEX--a (r)evolutionary method to generate high-affinity nucleic acid ligands.
Biomol Eng: 2007, 24(4);381-403
[PubMed:17627883] [WorldCat.org] [DOI] (P p)

@@ Line 9: / Line 9: @@
 </pubmed>
-== Ribozymes (catalytically active RNAs)==
+== Ribozymes (catalytically active RNAs)(Intro)==
 <pubmed>  	    21930582
 </pubmed>
-=== The Ribosome - the role and function of ribosomal RNAs     and the central dogma of molecular biology ===
+== The Ribosome - the role and function of ribosomal RNAs     and the central dogma of molecular biology ==
 <pubmed>  	    18292779		21930591		25500179
 </pubmed>
-=== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ===
+== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
 <pubmed>  	24452469		26682498		25798239
 </pubmed>
-=== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme and Co. ===
+== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
-<pubmed>  		22454536		14730013		10554775		21930585		6297745
+<pubmed>  22454536,14730013	10554775	21930585	6297745</pubmed>
-</pubmed>
 == RNA-based second messengers ==
-<pubmed>	28420751     25616065	25682701    25869574	 26280533</pubmed>
+<pubmed>28420751     25616065	25682701    25869574	 26280533</pubmed>
 == Riboregulation and virulence, targeting by antibiotics ==
@@ Line 55: / Line 54: @@
   <pubmed>         18981470      24667238 </pubmed>
-== RNAs as essential co-factors in protein enzymes ==
+== RNA dependent DNA Polymerases - from telomerase to retroviruses==
-=== RNA dependent DNA Polymerases - from telomerase to retroviruses===
 <pubmed>       18972389		26830230		    28141967
 </pubmed>
-=== RNA dependent RNA Polymerases – the RNA replicase ===
+== RNA dependent RNA Polymerases – the RNA replicase ==
 <pubmed>           29439438	    18268843		9878607
 </pubmed>
-=== CRISPR/Cas: Science – the bacterial “immune” system ===
+== CRISPR/Cas: Science – the bacterial “immune” system ==
 <pubmed>      29358495      29169146
      28375731</pubmed>
-=== CRISPR/Cas: Application and groundbreaking  perspectives ===
+== CRISPR/Cas: Application and groundbreaking  perspectives ==
 <pubmed>     26771484 </pubmed>
-=== The mysterious function and role of 6S-RNA and pRNA in bacteria ===
+== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
 <pubmed>     24786589  		17383220		24742053		23457253
 </pubmed>

Difference between revisions of "Stusti 2018"