Difference between revisions of "Stusti 2018"

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(CRISPR/Cas: Application)
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= Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas =
 
= Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas =
  
== Riboswitches ==
+
== What makes RNA such a special molecule – specific chemical and structural features of RNA ==
<pubmed>   27607554      26655897
+
<pubmed> 21930584
 +
</pubmed>
  
  28121427      29618088
+
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
    25794618    25794617
+
<pubmed>  24219496 8156586 28979293     26109351
 +
</pubmed>
  
 +
== Ribozymes (catalytically active RNAs)==
 +
<pubmed>      21930582  
 +
</pubmed>
  
 +
=== The Ribosome - the role and function of ribosomal RNAs    and the central dogma of molecular biology ===
 +
<pubmed>      18292779 21930591 25500179
 +
</pubmed>
  
  25848023    24769284
+
=== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ===
    25571850
+
<pubmed>  24452469 26682498 25798239
    25964329
+
</pubmed>
  
    26118534
+
=== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme and Co. ===
 +
<pubmed>  22454536 14730013 10554775 21930585 6297745
 +
</pubmed>
  
    26494285
+
== RNA-based second messengers ==
 
+
<pubmed> 28420751    25616065 25682701   25869574 26280533</pubmed>
  28206750  28375729    28396576   28541183    28455443
 
 
 
    29537923      27798597
 
 
 
    29135333 29420816  28611182</pubmed>
 
  
 
== Riboregulation and virulence, targeting by antibiotics ==
 
== Riboregulation and virulence, targeting by antibiotics ==
 
<pubmed>27651123      26416753
 
<pubmed>27651123      26416753
   27120414
+
   27120414   27672192  28434876  28529506 28886688</pubmed> 
  
  27672192  28434876  28529506 28886688</pubmed> 
+
== Riboswitches ==
 
+
<pubmed>   27607554     26655897   28121427      29618088 25794618     25794617 25848023     24769284 25571850   25964329   26118534 26494285 28206750   28375729    28396576   28541183    28455443   29537923      27798597 29135333  29420816   28611182</pubmed>
== RNA-based second messengers ==
 
<pubmed>28420751    25616065
 
 
 
     25682701
 
 
 
    25869574
 
 
 
  26280533</pubmed>    
 
 
 
== Ribozymes ==
 
<pubmed>27130889        15029187    18079181
 
 
 
     19781673  21848325
 
 
 
  24769284    28192411
 
 
 
  26481500     17624654  27408700
 
 
 
    27687155      20100492    27187488
 
 
 
   27863022
 
 
 
    28054987
 
 
 
   28620029   28697848   28733144
 
 
 
    28818345   28951565   26481500</pubmed>
 
  
 
== Protein- or tRNA-controlled RNA switches ==
 
== Protein- or tRNA-controlled RNA switches ==
 
<pubmed>25959893        24816551
 
<pubmed>25959893        24816551
 +
25583497</pubmed>
  
25583497</pubmed>
 
   
 
 
== RNA thermometers ==
 
== RNA thermometers ==
<pubmed>25477380</pubmed>
+
<pubmed>25477380 27060146 </pubmed>
   
+
 
 
 
== The RNA world and evolution ==
 
== The RNA world and evolution ==
<pubmed>      25109990
+
<pubmed>      25109990 25385129    25734234 25739364    26439358 17540026 29031737      28657884  19117371</pubmed>
  
  25385129    25734234
+
== RNA modification ==
     25739364   26439358
+
<pubmed>     26189113   26832457  27375676
 +
    28264529 28624569</pubmed>
  
  17540026
+
== RNA degradation/processing ==
  29031737      28657884
+
<pubmed>      26096689  28202538    19239894 </pubmed>  
  19117371</pubmed>
 
  
 +
== Regulation by non-coding RNA ==
 +
<pubmed>        18981470      24667238 </pubmed>
  
== RNA modification ==
+
== RNAs as essential co-factors in protein enzymes ==
<pubmed>     26189113    26832457  27375676
+
=== RNA dependent DNA Polymerases - from telomerase to retroviruses===
 +
<pubmed>      18972389 26830230     28141967
 +
</pubmed>  
  
     28264529
+
=== RNA dependent RNA Polymerases – the RNA replicase ===
 +
<pubmed>          29439438     18268843 9878607
 +
</pubmed>
  
  28624569</pubmed>
+
=== CRISPR/Cas: Science – the bacterial “immune” system ===
 +
<pubmed>      29358495      29169146
 +
    28375731</pubmed>
  
== RNA degradation/ processing ==
+
=== CRISPR/Cas: Application and groundbreaking  perspectives ===
<pubmed>       26096689  28202538</pubmed>
+
<pubmed>     26771484 </pubmed>  
  
== Regulation by non-coding RNA==
+
=== The mysterious function and role of 6S-RNA and pRNA in bacteria ===
<pubmed>         18981470
+
<pubmed>    24786589  17383220 24742053 23457253
 +
</pubmed>  
  
      24667238
+
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
 +
<pubmed>    22016848 26186290     21957054 23166520 21930591
 +
</pubmed>
  
 +
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
 +
<pubmed>        28533025 25561718 26883671
 +
    28485684 29182528 21925379
 
</pubmed>
 
</pubmed>
  
== CRISPR/Cas: Science ==
+
== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
<pubmed>     29358495      29169146
+
<pubmed>   17627883     19943183 
    28375731</pubmed>
+
</pubmed>
 
 
== CRISPR/Cas: Application ==
 
<pubmed>    26771484 </pubmed>
 

Revision as of 13:28, 22 June 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme and Co.


RNA-based second messengers


Riboregulation and virulence, targeting by antibiotics


Riboswitches


Protein- or tRNA-controlled RNA switches


RNA thermometers


The RNA world and evolution


RNA modification


RNA degradation/processing


Regulation by non-coding RNA



RNAs as essential co-factors in protein enzymes

RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways