Difference between revisions of "Toxins, antitoxins and immunity against toxins"
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* 4.3.1. [[General stress proteins (controlled by SigB)]] | * 4.3.1. [[General stress proteins (controlled by SigB)]] | ||
* 4.3.2. [[Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]] | * 4.3.2. [[Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]] | ||
− | * 4.3.3. [[Acid stress proteins (controlled by | + | * 4.3.3. [[Acid stress proteins (controlled by SigO-RsoA)]] |
* 4.3.4. [[Heat shock proteins]] | * 4.3.4. [[Heat shock proteins]] | ||
* 4.3.5. [[Cold stress proteins]] | * 4.3.5. [[Cold stress proteins]] | ||
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** [[BsrG]]/ [[SR4]] (= anti-''[[bsrG]]'') | ** [[BsrG]]/ [[SR4]] (= anti-''[[bsrG]]'') | ||
** [[YonT]]/ ''[[as-yonT]]'' | ** [[YonT]]/ ''[[as-yonT]]'' | ||
+ | |||
+ | * as part of the prophage-like element P6 | ||
+ | ** [[BsrE]]/ [[SR5]] | ||
===Type 2 TA systems:=== | ===Type 2 TA systems:=== | ||
* as part of [[SPß prophage]] | * as part of [[SPß prophage]] | ||
** [[SunA]]/ [[SunI]] | ** [[SunA]]/ [[SunI]] | ||
+ | |||
+ | * as part of the Skin element | ||
+ | ** [[YqcG]]-[[YqcF]] | ||
===Type 3 TA systems:=== | ===Type 3 TA systems:=== | ||
===Additional candidates=== | ===Additional candidates=== | ||
+ | * [[WapA]]/ [[WapI]] | ||
* ''[[ndoA]]'' | * ''[[ndoA]]'' | ||
* ''[[ndoAI]]'' | * ''[[ndoAI]]'' | ||
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* [[YobL]]-[[YobK]] | * [[YobL]]-[[YobK]] | ||
* [[YxiD]]-[[YxxD]] | * [[YxiD]]-[[YxxD]] | ||
− | |||
* [[YeeF]]-[[YezG]] | * [[YeeF]]-[[YezG]] | ||
* [[YwqJ]] | * [[YwqJ]] | ||
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==Key reviews== | ==Key reviews== | ||
− | <pubmed> 21041110 19493340 19325885 15864262 12970556 19052321 20156992 21315267 23059907 22434880 </pubmed> | + | <pubmed> 21041110 19493340 19325885 15864262 12970556 19052321 20156992 21315267 23059907 22434880 23289536 25808661</pubmed> |
=Back to [[categories]]= | =Back to [[categories]]= |
Latest revision as of 13:22, 28 January 2017
Parent categories |
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Neighbouring categories |
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Related categories |
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Contents
Classes of toxin/ antitoxin systems
- Type 1: toxic peptide/ antisense RNA
- Type 2: toxic protein/ antitoxin protein
- Type 3: toxic protein/ antagonistic RNA
Genes in this functional category
Type 1 TA systems:
Type 2 TA systems:
- as part of SPß prophage
Type 3 TA systems:
Additional candidates
Additional candidates (based on similarity)
Key reviews
Sabine Brantl, Natalie Jahn
sRNAs in bacterial type I and type III toxin-antitoxin systems.
FEMS Microbiol Rev: 2015, 39(3);413-27
[PubMed:25808661]
[WorldCat.org]
[DOI]
(I p)
Christopher F Schuster, Ralph Bertram
Toxin-antitoxin systems are ubiquitous and versatile modulators of prokaryotic cell fate.
FEMS Microbiol Lett: 2013, 340(2);73-85
[PubMed:23289536]
[WorldCat.org]
[DOI]
(I p)
Sylvain Durand, Natalie Jahn, Ciarán Condon, Sabine Brantl
Type I toxin-antitoxin systems in Bacillus subtilis.
RNA Biol: 2012, 9(12);1491-7
[PubMed:23059907]
[WorldCat.org]
[DOI]
(I p)
Tim R Blower, Francesca L Short, Feng Rao, Kenji Mizuguchi, Xue Y Pei, Peter C Fineran, Ben F Luisi, George P C Salmond
Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes.
Nucleic Acids Res: 2012, 40(13);6158-73
[PubMed:22434880]
[WorldCat.org]
[DOI]
(I p)
Tim R Blower, George P C Salmond, Ben F Luisi
Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxin-antitoxin partners.
Curr Opin Struct Biol: 2011, 21(1);109-18
[PubMed:21315267]
[WorldCat.org]
[DOI]
(I p)
Laurence Van Melderen
Toxin-antitoxin systems: why so many, what for?
Curr Opin Microbiol: 2010, 13(6);781-5
[PubMed:21041110]
[WorldCat.org]
[DOI]
(I p)
Elizabeth M Fozo, Kira S Makarova, Svetlana A Shabalina, Natalya Yutin, Eugene V Koonin, Gisela Storz
Abundance of type I toxin-antitoxin systems in bacteria: searches for new candidates and discovery of novel families.
Nucleic Acids Res: 2010, 38(11);3743-59
[PubMed:20156992]
[WorldCat.org]
[DOI]
(I p)
Kira S Makarova, Yuri I Wolf, Eugene V Koonin
Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.
Biol Direct: 2009, 4;19
[PubMed:19493340]
[WorldCat.org]
[DOI]
(I e)
Laurence Van Melderen, Manuel Saavedra De Bast
Bacterial toxin-antitoxin systems: more than selfish entities?
PLoS Genet: 2009, 5(3);e1000437
[PubMed:19325885]
[WorldCat.org]
[DOI]
(I p)
Elizabeth M Fozo, Matthew R Hemm, Gisela Storz
Small toxic proteins and the antisense RNAs that repress them.
Microbiol Mol Biol Rev: 2008, 72(4);579-89, Table of Contents
[PubMed:19052321]
[WorldCat.org]
[DOI]
(I p)
Kenn Gerdes, Susanne K Christensen, Anders Løbner-Olesen
Prokaryotic toxin-antitoxin stress response loci.
Nat Rev Microbiol: 2005, 3(5);371-82
[PubMed:15864262]
[WorldCat.org]
[DOI]
(P p)
Finbarr Hayes
Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest.
Science: 2003, 301(5639);1496-9
[PubMed:12970556]
[WorldCat.org]
[DOI]
(I p)