dtpT

dtpT
168

proton-dependent di- and tripeptide transporter

Locus
BSU_03670
Molecular weight
53.11 kDa
Isoelectric point
9.92
Protein length
492 aaSequenceBlast
Gene length
1479 bpSequenceBlast
Function
uptake of di- and tripeptides
Product
peptide transporter
Essential
no
Synonyms
dtpT, yclF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3104 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
416,235  417,713
The protein
Protein family
PTR2/POT transporter (TC 2.A.17) family (single member, according to UniProt)
Structure
4IKV (PDB), the protein from Geobacillus kaustophilus (65% identity, 87% similarity), PubMed
P94408 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
dtpT
Description
PubMed
Regulation
repressed during exponential growth (ScoC) PubMed
Regulatory mechanism
ScoC: repression, PubMed, in scoC regulon
TnrA: activation, in tnrA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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dtpT

2025-03-17 18:32:37

Jstuelk

60

7c22b9931473697cfcb62d0db1bf4661fa8775df

A5B1DFD7663E2A4943E9333E95C6217065E61488

Additional information
the mRNA is cleaved by RNase III PubMed
Biological materials
Mutant
BKE03670 (dtpT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC,  downstream forward: _UP4_TAATCAGAAACAGCCCGCGG
BKK03670 (dtpT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCAGCCAAACCCTTTC,  downstream forward: _UP4_TAATCAGAAACAGCCCGCGG
References
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Time of last update: 2025-04-06 22:06:52

Author of last update: Melvin.boenninger