Difference between revisions of "Elongasome"
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==Back to [[SubtInteract]]== | ==Back to [[SubtInteract]]== | ||
Latest revision as of 15:33, 7 July 2015
A protein complex that catalyzes peptidoglycan biosynthesis and is thereby involved in maintaining cell shape
Contents
Complex members
- cell wall biosynthetic enzymes at the outer side of the membrane: penicillin-binding proteins (PbpA, PbpH, perhaps also PbpC, DacC, PbpI)
- transmembrane proteins: MreC, MreD, RodA, RodZ, they couple the cytosolic actin-like proteins to the extracellular peptidoglycan-synthesizing machinery
- actin-like proteins at the inner surface of the membrane: MreB, MreBH, Mbl, the polymers control/restrict the mobility of the cell wall elongation enzyme complex
Related pages
Labs working on the complex
- Rut Carballido-Lopez, Jouy-en-Josas
- Jeff Errington, Newcastle upon Tyne
- David Rudner, New York
Important publications
Alexander J F Egan, Waldemar Vollmer
The stoichiometric divisome: a hypothesis.
Front Microbiol: 2015, 6;455
[PubMed:26029191]
[WorldCat.org]
[DOI]
(P e)
Piotr Szwedziak, Jan Löwe
Do the divisome and elongasome share a common evolutionary past?
Curr Opin Microbiol: 2013, 16(6);745-51
[PubMed:24094808]
[WorldCat.org]
[DOI]
(I p)
Orietta Massidda, Linda Nováková, Waldemar Vollmer
From models to pathogens: how much have we learned about Streptococcus pneumoniae cell division?
Environ Microbiol: 2013, 15(12);3133-57
[PubMed:23848140]
[WorldCat.org]
[DOI]
(I p)
Andrew Jermy
Bacterial physiology: MreB takes a back seat.
Nat Rev Microbiol: 2011, 9(8);560-1
[PubMed:21725336]
[WorldCat.org]
[DOI]
(I e)
Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745]
[WorldCat.org]
[DOI]
(I p)
Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744]
[WorldCat.org]
[DOI]
(I p)
