panU

panU
168

S protein of pantothenate ECF transporter

Locus
BSU_10370
Molecular weight
19.87 kDa
Isoelectric point
10.68
Protein length
186 aaSequenceBlast
Gene length
561 bpSequenceBlast
Function
uptake of pantothenate
Product
S protein of pantothenate ECF transporter
Essential
no
Synonyms
yhfU, bioY
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1268 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,111,925  1,112,485
The protein
Catalyzed reaction/ biological activity
uptake of pantothenate PubMed
Protein family
bioY family (with YuiG, according to UniProt)
Structure
4DVE (PDB) (BioY from Lactococcus lactis, 35% identity, 71% similarity) PubMed
O07620 (AlphaFold)
Localization
membrane associated PubMed
Expression and Regulation
Operons
Genes
panU-yhfT-yhfS-yhfR
Description
PubMed
Regulation
repressed in the presence of biotin (BirA) PubMed
Regulatory mechanism
BirA: repression, PubMed, in birA regulon
Additional information
weakly expressed PubMed
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panU→yhfR

2025-03-16 18:29:48

ghost

116

89c1778bebc3b239c3d7430040a2e0383ed84687

B42B3F0DE33D475226AC600D1867A0778BBB154A

Biological materials
Mutant
GP4704 (trpC2 ΔpanU::neo), available in Jörg Stülke's lab PubMed
MGNA-B281 (yhfU::erm), available at the NBRP B. subtilis, Japan
BKE10370 (panU::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGAAATCCTCCAAAAA,  downstream forward: _UP4_TTTACAAAAGGAGGATGACA
BKK10370 (panU::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGAAATCCTCCAAAAA,  downstream forward: _UP4_TTTACAAAAGGAGGATGACA
References
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Page visits: 6009

Time of last update: 2025-04-07 05:02:31

Author of last update: Jstuelk