conE

conE
168

ATPase, required for conjugation of ICEBs1, part of the type IV secretion system for DNA transfer

Locus
BSU_04940
Molecular weight
96.06 kDa
Isoelectric point
5.51
Protein length
797 aaSequenceBlast
Gene length
2394 bpSequenceBlast
Function
conjugative transfer of ICEBs1
Product
ATPase, part of the type IV secretion system for DNA transfer
Essential
no
E.C.
null
Synonyms
conE, yddE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3451 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
538,836 → 541,229
Phenotypes of a mutant
Defective for conjugal transfer of ICE''Bs1
The protein
Catalyzed reaction/ biological activity
required for conjugative transfer of ICEBs1, putative ATPase PubMed
Protein family
HerA/FtsK Superfamily of ATPases including the well-studied proteins FtsK, SpoIIIE, VirB4, and VirD4
Structure
P96642 (AlphaFold)
Localization
peripheral membrane protein (via ConB), located at the cell poles PubMed
Expression and Regulation
Operons
Genes
xis-ydzL-devI-ydcP-ydcQ-nicK-S172-ramS-ramT-ramA-conB-conC-conD-conE-yddF-conG-cwlT-yddI-yddJ
Description
PubMed
Regulatory mechanism
ImmR: repression, PubMed, in immR regulon
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xis->yddJ

2025-04-04 00:35:31

Bzhu

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9225e26ee70027d168e8ea0db13fb48c93ef1ef8

DE8D2BDC2F23AB45C58B0FE511E7B4816A65A489

Biological materials
Mutant
BKE04940 (ΔconE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTTTTATACGATTCAACTT,  downstream forward: _UP4_TTGTAAAAAGGGGTTGAATC
BKK04940 (ΔconE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTTTTATACGATTCAACTT,  downstream forward: _UP4_TTGTAAAAAGGGGTTGAATC
Labs working on this gene/protein
Melanie Barker Berkmen, Suffolk University, Boston, MA Homepage
References
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Time of last update: 2025-04-07 01:54:10

Author of last update: Jstuelk