spoVB

spoVB
168

MurJ family lipid II flippase, spore cortex peptidoglycan synthesis

Locus
BSU_27670
Molecular weight
55.91 kDa
Isoelectric point
10.19
Protein length
518 aaSequenceBlast
Gene length
1557 bpSequenceBlast
Function
spore cortex peptidoglycan synthesis
Product
sporulation-specific MurJ family lipid II flippase
Essential
no
Synonyms
spoVB, spoIIIF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5841 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,829,564  2,831,120
The protein
Protein family
Polysaccharide synthase family (according to UniProt)
MOP exporter family
Structure
Q00758 (AlphaFold)
Paralogous protein(s)
YabM, MurJ, YkvU
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
spoVB-yrzE
Description
PubMed
Regulation
expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed
Regulatory mechanism
SpoIIID: repression, PubMed, in spoIIID regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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spoVB→yrzE

2025-04-05 06:06:42

Jstuelk

97

3d9cf008322b4a86befb1b7390b388e393ab9266

EBC3D6455890919A760BCEF30508470C1A334950

Biological materials
Mutant
BKE27670 (spoVB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC,  downstream forward: _UP4_GGACGGTTGATCATCCGATA
BKK27670 (spoVB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC,  downstream forward: _UP4_GGACGGTTGATCATCCGATA
References
Reviews
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Original Publications
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9633C40190B7D0EA264270FD44567C61A012AD15

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Time of last update: 2025-04-06 22:09:38

Author of last update: Jstuelk