yloH

yloH
168

omega subunit of RNA polymerase

Locus
BSU_15690
Molecular weight
7.62 kDa
Isoelectric point
5.51
Protein length
67 aaSequenceBlast
Gene length
204 bpSequenceBlast
Function
unknown
Product
omega subunit of RNA polymerase
Essential
no
E.C.
2.7.7.6
Synonyms
yloH, rpoZ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1758 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,642,567  1,642,770
The protein
Catalyzed reaction/ biological activity
ribonucleoside 5'-triphosphate + RNA(n) --> diphosphate + RNA(n+1) (according to UniProt)
Protein family
RNA polymerase subunit omega family (single member, according to UniProt)
Structure
6WVJ (PDB) (RNA polymerase elongation complex, RpoA-RpoB-RpoC-YloH) PubMed
5UH5 (PDB) (transcription initiation complex from Mycobacterium tuberculosis, 37% identity, aa 1- 52) PubMed
O35011 (AlphaFold)
Localization
closely associated with RNA polymerase involved in transcribing both mRNA and rRNA operons PubMed
Expression and Regulation
Operons
Genes
yloC-remA-gmk-yloH
Description
PubMed
Regulation
expressed during vegetative growth and early during sporulation in the forespore (SigF) PubMed
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
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yloC->yloH

2025-04-04 08:01:09

Bzhu

143

b4ed2f235ea58a2cb7be55cafee822b895fe00c8

099190FEE74E539BB75FE227F5793536D7B467E8

Genes
yloC-remA-gmk-yloH-coaBC-priA-defA-fmt-yloM-yloN
Description
PubMed
Open in new tab

yloC->yloN

2025-04-04 08:04:53

Jstuelk

155

67080d1e476b4c1544f46abe5db9b45c3ccd93f3

2C39B75EDCD294B0CAC1DECB4007285A35FDAE1D

Genes
yloB-yloC-remA-gmk-yloH
Description
PubMed
Regulation
expressed during sporulation in the mother cell PubMed
Open in new tab

yloB->yloH

2025-04-03 13:34:29

Jstuelk

150

b15c1f28629d3e15db14719be44c291dd5f28c5f

86CE620BD4E14CC259270F542702B302B7837CCD

Biological materials
Mutant
BKE15690 (yloH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCAATTGACGGATCTAACA,  downstream forward: _UP4_TAGTAGCACAAGTAGCAACC
BKK15690 (yloH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCAATTGACGGATCTAACA,  downstream forward: _UP4_TAGTAGCACAAGTAGCAACC
References
Reviews
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Original Publications
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921933B6B893083F151AABDEDCBC65F2E55677BE

Page visits: 3604

Time of last update: 2025-04-07 03:09:52

Author of last update: Jstuelk