cotY

cotY
168

main structural component of the spore crust, necessary for the assembly of the spore crust, the outermost layer of the spore coat

Locus
BSU_11750
Molecular weight
17.74 kDa
Isoelectric point
4.86
Protein length
162 aaSequenceBlast
Gene length
489 bpSequenceBlast
Function
spore crust assembly
Product
spore crust protein (insoluble fraction)
Essential
no
Synonyms
cotY
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5888 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,250,016 → 1,250,504
The protein
Structure
Q08311 (AlphaFold)
Paralogous protein(s)
CotZ
Localization
spore crust PubMed
localization requires CotZ PubMed
Expression and Regulation
Operons
Genes
cotY-cotZ
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigK) PubMed
Regulatory mechanism
GerR: activation, PubMed, in gerR regulon
GerE: activation, PubMed, in gerE regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
SigE: sigma factor, PubMed, in sigE regulon
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cotY→cotZ

2025-03-31 09:17:47

ghost

58

d5352cc528c9d84dd78f9c0efc66e2b6f4d516ce

FC77A0E4A305752E4BFB18C6B5B61BE0A0A39C5D

Biological materials
Mutant
BKE11750 (ΔcotY::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGATTTCAGCTCCTTCT,  downstream forward: _UP4_TAAACACTTGTAAAGAGGAA
BKK11750 (ΔcotY::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGATTTCAGCTCCTTCT,  downstream forward: _UP4_TAAACACTTGTAAAGAGGAA
References
Reviews
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Original Publications
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B2636947990A303C43CEA8BFBE38811DD233A0A6

Page visits: 4095

Time of last update: 2025-04-06 16:47:13

Author of last update: Jstuelk