nudF

nudF
168

involved in isopentenol (isoprenoid) biosynthesis, has RNA pyrophosphohydrolase activity

Locus
BSU_23610
Molecular weight
20.84 kDa
Isoelectric point
4.59
Protein length
185 aaSequenceBlast
Gene length
558 bpSequenceBlast
Function
isoprenoid biosynthesis
Product
unknown
Essential
no
E.C.
3.6.1.13
Synonyms
nudF, yqkG
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0494 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,458,509 → 2,459,066
The protein
Catalyzed reaction/ biological activity
ADP-D-ribose + H2O --> AMP + D-ribose 5-phosphate + 2 H+ (according to UniProt)
Protein family
Nudix hydrolase (according to UniProt)
Domains
Nudix hydrolase domain (aa 40-171) (according to UniProt)
Structure
1V8I (PDB) (from Thermus thermophilus, 38% identity) PubMed
P54570 (AlphaFold)
Expression and Regulation
Operons
Genes
nudF-yqxK
Description
PubMed
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nudF→yqxK

2025-03-09 10:27:33

ghost

66

737730cf7bae42c0c0ad7d0fb39c2b9d08adfec7

8E269580575F39E0B9C3EB7C9D2AA8006F37B9DA

Biological materials
Mutant
MGNA-C410 (yqkG::erm), available at the NBRP B. subtilis, Japan
BKE23610 (ΔnudF::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCTTCATCTCCCGTTC,  downstream forward: _UP4_AAAGAAGCGCTCCAAGCACA
BKK23610 (ΔnudF::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCTTCATCTCCCGTTC,  downstream forward: _UP4_AAAGAAGCGCTCCAAGCACA
References
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Time of last update: 2025-04-10 04:48:05

Author of last update: Jstuelk