Difference between revisions of "GerT"

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* '''Description:''' write here <br/><br/>
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* '''Description:''' spore coat protein, involved in germination <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yozR''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yozR''
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Essential''' ||  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' ||  
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|style="background:#ABCDEF;" align="center"| '''Product''' || spore coat protein
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || germination
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|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19490 gerT]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 6.342   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 6.342   
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 471 bp, 157 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 471 bp, 157 aa  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' ||  
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yojE]]'', ''[[yojB]]''
 
|-
 
|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yozR_nucleotide.txt    Gene sequence     (+200bp)  ]'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19490 DNA_with_flanks]
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yozR_protein.txt Protein sequence]'''
 
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yozR_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yozR_context.gif]]
 +
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 +
|-
 +
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerT_2124021_2124494_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gerT_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19490]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/>
  
−
<br/><br/>
+
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[sporulation proteins]]}},
 +
{{SubtiWiki category|[[germination]]}},
 +
{{SubtiWiki category|[[membrane proteins]]}}
 +
 
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[SigK regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Basic information ===
 
=== Basic information ===
  
−
* '''Coordinates:'''
+
* '''Locus tag:''' BSU19490
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
−
 
+
* mutants respond poorly to multiple germinants, impaired in early stage of germination {{PubMed|17720779}}
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19490&redirect=T BSU19490]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yozR.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yozR.html]
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=== Additional information===
 
=== Additional information===
 +
 +
  
  
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
−
* '''Protein family:'''
+
* '''Protein family:''' eamA transporter family (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
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* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''
  
−
* '''Localization:'''
+
* '''[[Localization]]:'''
 +
** cell membrane (according to Swiss-Prot), first assembled in foci, then spread around the developing spore in a [[CotE]]-dependent manner {{PubMed|17720779}}
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19490&redirect=T BSU19490]
  
 
* '''Structure:'''
 
* '''Structure:'''
  
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* '''Swiss prot entry:'''
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q7WY67 Q7WY67]
  
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* '''KEGG entry:'''
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU19490]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
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=Expression and regulation=
 
=Expression and regulation=
  
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* '''Operon:'''  
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* '''Operon:''' ''gerT'' {{PubMed|22383849}}
  
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* '''Sigma factor:'''  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerT_2124021_2124494_1 gerT] {{PubMed|22383849}}
 +
 
 +
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|17720779}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|17720779}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription repression {{PubMed|17720779}}
  
−
* '''Additional information:'''  
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* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
  
−
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
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<pubmed>,17720779, </pubmed>
 +
 
 +
[[Category:Protein-coding genes]]

Latest revision as of 13:59, 6 April 2015

  • Description: spore coat protein, involved in germination

Gene name gerT
Synonyms yozR
Essential no
Product spore coat protein
Function germination
Gene expression levels in SubtiExpress: gerT
MW, pI 18 kDa, 6.342
Gene length, protein length 471 bp, 157 aa
Immediate neighbours yojE, yojB
Sequences Protein DNA DNA_with_flanks
Genetic context
YozR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GerT expression.png















Categories containing this gene/protein

sporulation proteins, germination, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU19490

Phenotypes of a mutant

  • mutants respond poorly to multiple germinants, impaired in early stage of germination PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: eamA transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot), first assembled in foci, then spread around the developing spore in a CotE-dependent manner PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Caitlin C Ferguson, Amy H Camp, Richard Losick
gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(21);7681-9
[PubMed:17720779] [WorldCat.org] [DOI] (P p)

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