Difference between revisions of "CotU"

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(→‎Extended information on the protein)
(→‎Expression and regulation)
 
(18 intermediate revisions by 5 users not shown)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17670 cotU]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=CotU CotU]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 6.315   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 6.315   
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 258 bp, 86 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 258 bp, 86 aa  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yncF]]'', ''[[thyA]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yncF]]'', ''[[ynzJ]]''
 
|-
 
|-
−
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13651&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17670 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ynzH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ynzH_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 +
|-
 +
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:cotU_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17670]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/>
  
−
<br/><br/>
+
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[sporulation proteins]]}}
 +
 
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[GerE regulon]]}},
 +
{{SubtiWiki regulon|[[GerR regulon]]}},
 +
{{SubtiWiki regulon|[[SigK regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17670&redirect=T BSU17670]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
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=== Additional information===
 
=== Additional information===
 +
 +
  
  
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
−
* '''Interactions:''' [[CotC]]-[[CotU]] {{PubMed|18065538}},  [[CotE]]-[[CotU]] {{PubMed|20023017}}
+
* '''[[SubtInteract|Interactions]]:'''
 +
** [[CotC]]-[[CotU]] {{PubMed|18065538}},  [[CotE]]-[[CotU]] {{PubMed|20023017}}
  
−
* '''Localization:''' the [[CotC]]-[[CotU]] complex assembles around the forming spore {{PubMed|18065538}}
+
* '''[[Localization]]:'''  
 +
** outer spore coat, localization depends on [[CotE]]  {{PubMed|22171814}}
 +
** the [[CotC]]-[[CotU]] complex assembles around the forming spore {{PubMed|18065538}}
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17670&redirect=T BSU17670]
  
 
* '''Structure:'''
 
* '''Structure:'''
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=Expression and regulation=
 
=Expression and regulation=
  
−
* '''Operon:'''  
+
* '''Operon:''' ''cotU'' {{PubMed|22383849}}
  
−
* '''[[Sigma factor]]:'''  
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 cotU] {{PubMed|22383849}}
 +
 
 +
* '''Sigma factor:''' [[SigK]] {{PubMed|18065538}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
−
** [[GerR]]: transcription repression {{PubMed|20435725}}
+
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|18065538}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription activation {{PubMed|18065538}}
 +
** [[GerR]]: transcription repression {{PubMed|20435725}}
  
−
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
  
−
<pubmed>18065538,12562816, 20023017,20435725 </pubmed>
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<pubmed>18065538,12562816, 20023017,20435725 22171814</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Latest revision as of 13:50, 6 April 2015

  • Description: spore coat protein

Gene name cotU
Synonyms ynzH
Essential no
Product spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotU
Interactions involving this protein in SubtInteract: CotU
MW, pI 11 kDa, 6.315
Gene length, protein length 258 bp, 86 aa
Immediate neighbours yncF, ynzJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YnzH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotU expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, GerR regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU17670

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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