cotB

cotB
168

spore coat protein (outer)

Locus
BSU_36050
Molecular weight
42.81 kDa
Isoelectric point
9.83
Protein length
380 aaSequenceBlast
Gene length
1143 bpSequenceBlast
Function
resistance of the spore
Product
spore coat protein (outer)
Essential
no
Synonyms
cotB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
3,714,739  3,715,881
The protein
Structure
P07789 (AlphaFold)
Modification
phosphorylated on serine residues by CotH PubMed
maturation of CotB requires CotG PubMed
Localization
outer spore coat, at the middle of the spore as a ring- or spiral-like structure, localization depends on CotE  PubMed
Expression and Regulation
Operons
Genes
cotH-cotB-ywrJ
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigE, SigK, GerE, SpoIIID) PubMed
Regulatory mechanism
GerR: activation, PubMed, in gerR regulon
GerE: repression, PubMed, in gerE regulon
SpoIIID: activation, PubMed, in spoIIID regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
SigE: sigma factor, PubMed, in sigE regulon
Open in new tab

cotH→ywrJ

2025-04-13 18:49:33

ghost

105

522d2dc3540a057ccb4247a51bdcef8f2aab470a

03DF2C1A39CB01A4DB9919D07A586C7F244BEAFF

Genes
cotB-ywrJ
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigE, SigK, GerE, GerR) PubMed
Open in new tab

cotB→ywrJ

2025-04-10 00:05:39

ghost

70

e1a7dfcab37c895cf68952c400b3c5dda66e8c33

70EF1AF9FFB64263BEFC2CDD5247BE6F97FE1D3F

Biological materials
Mutant
1S102 ( cotB::cat), PubMed, available at BGSC
BKE36050 (cotB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC,  downstream forward: _UP4_TAATAGATAATGGAGGAGCA
BKK36050 (cotB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC,  downstream forward: _UP4_TAATAGATAATGGAGGAGCA
References
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2A0B2CA7C982C03C1AFBDB3540A918EE937B06CB

Page visits: 7199

Time of last update: 2025-04-14 08:41:21

Author of last update: Jstuelk