csfB

csfB
168

anti-sigma factor, inhibitor of SigG and of SigE

Locus
BSU_00240
Molecular weight
7.30 kDa
Isoelectric point
7.67
Protein length
64 aaSequenceBlast
Gene length
195 bpSequenceBlast
Function
control of SigG and SigE activity
Product
inhibitor of SigG and SigE
Essential
no
Synonyms
csfB, gin, yaaM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5865 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
35,531  35,725
Phenotypes of a mutant
premature activation of SigG PubMed
The protein
Catalyzed reaction/ biological activity
inhibitor of SigG and SigE PubMed
Cofactors
Zn2+ PubMed
Structure
5N7Y (PDB) PubMed
P37534 (AlphaFold)
Localization
forespore and mother cell PubMed
Expression and Regulation
Operons
Genes
csfB
Description
PubMed
Regulation
expressed after completion of forespore engulfment in the mother cell (SigK) PubMed
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
SigK: sigma factor, PubMed, in sigK regulon
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csfB

2025-04-04 05:34:11

ghost

102

e30a7126916b4c8c4e3e5c12249bb352e2475d91

D21B71FF00AEAF52623DD34B50DECA0BD8426A91

Biological materials
Mutant
MGNA-B894 (yaaM::erm), available at the NBRP B. subtilis, Japan
BKE00240 (csfB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTCTCCACCTCCGTAC,  downstream forward: _UP4_TAGACCTGAAAAGGTCTTTT
BKK00240 (csfB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTCTCCACCTCCGTAC,  downstream forward: _UP4_TAGACCTGAAAAGGTCTTTT
References
Reviews
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Original Publications
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01412FA454DDBA12622E3B32C433F8059123661B

Page visits: 4188

Time of last update: 2025-04-07 04:31:27

Author of last update: Jstuelk