bmr

bmr
168

general stress protein, multidrug-efflux transporter

Locus
BSU_24010
Molecular weight
42.10 kDa
Isoelectric point
9.7
Protein length
389 aaSequenceBlast
Gene length
1170 bpSequenceBlast
Function
multidrug resistance
Product
multidrug-efflux transporter
Essential
no
Synonyms
bmr, bmr1
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,494,656  2,495,825
The protein
Protein family
major facilitator superfamily (according to UniProt)
TCR/Tet family (according to UniProt)
Structure
P33449 (AlphaFold)
Paralogous protein(s)
Blt
Expression and Regulation
Operons
Genes
bmr-bmrR
Description
PubMed
Regulation
''bmrU'': induced by stress (SigB) PubMed
Regulatory mechanism
BmrR: activation, PubMed, in bmrR regulon
Mta: activation, PubMed, in mta regulon
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

bmr→bmrR

2025-04-06 01:46:23

ghost

68

b2678c97b26f06ae18b1a6202a13a471a29089dd

8BB3E68CAC61180C1796BD46F562DE5C5EEC5434

Genes
bmrU-bmr-bmrR
Description
PubMed
Regulation
''bmrU'': induced by stress (SigB) PubMed
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
Open in new tab

bmrU→bmrR

2025-04-05 23:31:41

ghost

81

2e647ad1226b497eeb1c22896849b452c0b79a82

C61FA43F89F0BEC555BDAD8ACACFBD6D473F57AD

Biological materials
Mutant
BKE24010 (bmr::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGACTTCCCCTTTTTC,  downstream forward: _UP4_TGATAAGAAGCGCATTCTTT
BKK24010 (bmr::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGACTTCCCCTTTTTC,  downstream forward: _UP4_TGATAAGAAGCGCATTCTTT
References
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ADBC0F194B601F736492E54011E0A68351B5BD39

Page visits: 4319

Time of last update: 2025-04-13 07:46:54

Author of last update: Melvin.boenninger