Difference between revisions of "Prp"

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m (Jstuelk moved page YsxB to Prp: 25388641)
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* '''Description:''' unknown <br/><br/>
+
* '''Description:''' protein cysteine protease, required for N-terminal cleavage of ribosomal protein [[rpmA|L27]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ysxB''
+
|''prp''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ysxB ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[rpmA|L27]] protein cysteine protease
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of [[rpmA|L27]]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27950 ysxB]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27950 prp]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 4.456   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 4.456   
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}}
+
{{SubtiWiki category|[[translation]]}},
 +
{{SubtiWiki category|[[proteolysis]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** N-terminal cleavage of ribosomal protein [[rpmA|L27]] {{PubMed|25388641}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''  
  
* '''Localization:'''
+
* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
 
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27950&redirect=T BSU27950]
 
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27950&redirect=T BSU27950]
  
* '''Structure:'''
+
* '''Structure:''' [http://pdb.org/pdb/explore/explore.do?structureId=2P92 2P92] (the protein from ''S. aureus'')
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P26942 P26942]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P26942 P26942]
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=References=
 
=References=
<pubmed> 11948165</pubmed>  
+
<pubmed> 11948165 25388641 </pubmed>  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:30, 10 December 2014

  • Description: protein cysteine protease, required for N-terminal cleavage of ribosomal protein L27

Gene name prp
Synonyms ysxB
Essential no
Product L27 protein cysteine protease
Function maturation of L27
Gene expression levels in SubtiExpress: prp
MW, pI 12 kDa, 4.456
Gene length, protein length 336 bp, 112 aa
Immediate neighbours rpmA, rplU
Sequences Protein DNA DNA_with_flanks
Genetic context
YsxB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YsxB expression.png















Categories containing this gene/protein

translation, proteolysis

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU27950

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • N-terminal cleavage of ribosomal protein L27 PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 2P92 (the protein from S. aureus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References