Difference between revisions of "SinR regulon"

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(Repression)
 
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Regulator=[[SinR]]
 
Regulator=[[SinR]]
 
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}}
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* SinR may act as transcriptional repressor at some promoters (as for the ''[[tapA]]'' promoter) and as anti-activator preventing binding of [[RemA]] for other operons (as is the case for the ''[[epsA]]'' promoter)  {{PubMed|23646920}}
  
 
= Genes in this regulon =
 
= Genes in this regulon =
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=== Repression ===
 
=== Repression ===
 
* ''[[aprE]]''
 
* ''[[aprE]]''
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* ''[[degU]]''
 
* ''[[epr]]''
 
* ''[[epr]]''
* ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
 
 
* ''[[lutA]]-[[lutB]]-[[lutC]]''
 
* ''[[lutA]]-[[lutB]]-[[lutC]]''
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* ''[[mstX]]''
 
* ''[[rapG]]''
 
* ''[[rapG]]''
 
* ''[[rok]]''
 
* ''[[rok]]''
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* ''[[spoVG]]''
 
* ''[[spoVG]]''
 
* ''[[tapA]]-[[sipW]]-[[tasA]]''
 
* ''[[tapA]]-[[sipW]]-[[tasA]]''
 +
* ''[[yugO]]''
 
* ''[[yvgN]]''
 
* ''[[yvgN]]''
 
* ''[[ywbD]]''
 
* ''[[ywbD]]''
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 +
=== Anti-activation (Prevention of binding of the activator protein [[RemA]]) ===
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* ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
  
 
= Comments =
 
= Comments =
 
* The [[SinR]] regulon is not expressed in ''[[rny]]'' and ''[[ymdB]]'' mutants {{PubMed|21856853,21815947}}  
 
* The [[SinR]] regulon is not expressed in ''[[rny]]'' and ''[[ymdB]]'' mutants {{PubMed|21856853,21815947}}  
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* Expression of the [[SinR regulon]] is enhanced upon [[SlrA]] overexpression, this can be suppressed by inactivation of either ''[[remA]]'', ''[[remB]]'', ''[[slrR]]'', or ''[[sinR]]'' {{PubMed|22329926}}
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* Expression of the [[SinR regulon]] is enhanced in a ''[[rpsU]]'' mutant, this can be suppressed by inactivation of ''[[remA]]'' {{PubMed|25035996}}
  
 
= Related ''Subti''Wiki pages=
 
= Related ''Subti''Wiki pages=
 
* [[biofilm formation]]
 
* [[biofilm formation]]
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* [[RemA regulon]]
  
 
= Important publications on the [[SinR]] regulon =
 
= Important publications on the [[SinR]] regulon =
<big>''Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J''  </big>
+
<pubmed>18763711,19193632,17005971 19779461 19820159 20418391 20525796 20572937,21803996 21843271 22329926 21856853 21815947 25035996 16430695</pubmed>
<big>'''A Novel Factor Controlling Bistability in ''Bacillus subtilis'': The YmdB Protein Affects</big>
 
<big>Flagellin Expression and Biofilm Formation.''' </big>
 
J Bacteriol. 2011 Aug 19. [Epub ahead of print]
 
[http://www.ncbi.nlm.nih.gov/pubmed/21856853 PubMed:21856853]
 
  
<big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J''  </big>
 
<big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big>
 
<big>Mol Microbiol. 2011 Aug 4. doi: 10.1111/j.1365-2958.2011.07777.x. [Epub ahead of print] </big>
 
[http://www.ncbi.nlm.nih.gov/pubmed/21815947 PubMed:21815947]
 
<pubmed>18763711,19193632,17005971 19779461 19820159 20418391 20525796 20572937,21803996 21843271 </pubmed>
 
<pubmed>16430695,</pubmed>
 
 
=Back to [[regulons]]=
 
=Back to [[regulons]]=

Latest revision as of 14:29, 30 November 2014

Regulator

SinR

  • SinR may act as transcriptional repressor at some promoters (as for the tapA promoter) and as anti-activator preventing binding of RemA for other operons (as is the case for the epsA promoter) PubMed

Genes in this regulon

Repression

Anti-activation (Prevention of binding of the activator protein RemA)

Comments

Related SubtiWiki pages

Important publications on the SinR regulon


Back to regulons