yxkO

yxkO
168

ADP/ATP-dependent NAD(P)H-hydrate dehydratase, general stress protein, survival of ethanol stress

Locus
BSU_38720
Molecular weight
29.72 kDa
Isoelectric point
5.49
Protein length
276 aaSequenceBlast
Gene length
831 bpSequenceBlast
Function
survival of ethanol stress, repair of hydrated NAD(P)H
Product
ADP/ATP-dependent NAD(P)H-hydrate dehydratase
Essential
no
Synonyms
yxkO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0063 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,972,448  3,973,278
The protein
Catalyzed reaction/ biological activity
(6S)-NADHX + ADP --> AMP + H+ + NADH + phosphate (according to UniProt)
(6S)-NADPHX + ADP --> AMP + H+ + NADPH + phosphate (according to UniProt)
Protein family
NnrD/CARKD family (single member, according to UniProt)
Domains
YjeF C-terminal domain (aa 7-275) (according to UniProt)
Structure
1KYH (PDB) PubMed
P94368 (AlphaFold)
Expression and Regulation
Operons
Genes
yxkO
Description
PubMed
Regulation
induced by stress (SigB) PubMed
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
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yxkO

2025-03-15 02:28:25

ghost

59

72b1bb9a168ed6ea856c7c3616f316618df3fedc

EE523300911EC1E7DDDE06FEC097C7AEB6560535

Biological materials
Mutant
MGNA-B749 (yxkO::erm), available at the NBRP B. subtilis, Japan
BKE38720 (yxkO::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCTATCCCTCCTCTGC,  downstream forward: _UP4_TTTGAATGATAAAAAAGCTG
BKK38720 (yxkO::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCTATCCCTCCTCTGC,  downstream forward: _UP4_TTTGAATGATAAAAAAGCTG
References
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0A9C77804C09CD5E7D1D5D274E01B5B14920A1A9

Page visits: 2847

Time of last update: 2025-03-30 15:15:30

Author of last update: Melvin.boenninger