liaH

liaH
168

similar to phage shock protein, resistance against oxidative stress and cell wall antibiotics (such as daptamycin), secondary bacitracin resistance determinant, accessory subunit of the TatAY-TatCY protein secretion complex

Locus
BSU_33120
Molecular weight
25.55 kDa
Isoelectric point
6.17
Protein length
225 aaSequenceBlast
Gene length
678 bpSequenceBlast
Function
resistance against oxidative stress and cell wall antibiotics, protein secretion
Product
accessory subunit of the TatAY-TatCY protein secretion complex
Essential
no
Synonyms
liaH, yvqH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1842 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,397,846  3,398,523
The protein
Protein family
pspA/IM30 family (with PspA, according to UniProt)
Structure
O32201 (AlphaFold)
Paralogous protein(s)
PspA
Localization
variable (spotty) protein PubMed
throughout the cytoplasm under non-inducing conditions PubMed
co-localizes with LiaI in distinct static spots at the cytoplasma membrane under stress conditions PubMed
Expression and Regulation
Operons
Genes
liaI-liaH
Description
PubMed
Regulation
induced by bacitracin and rhamnolipids, induction requires high bacitracin concentrations (LiaR) PubMed
Regulatory mechanism
LiaR: activation, PubMed, in liaR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

liaI→liaH

2025-04-09 00:20:12

ghost

83

4515f9113aa08a654b32efa8559976dff13218b4

88031D8530F9F98EF75C918C1D47EDBCF9DEBB70

Genes
liaI-liaH-liaG-liaF-liaS-liaR
Description
PubMed
Regulation
''liaG'': constitutive
Open in new tab

liaI→liaR

2025-04-10 02:31:07

ghost

128

844f52131490c84c9a0558a221a24520579ef3fd

F37C9323D2117C9590CDC8EC3E6B0E3F58AFC1F7

Biological materials
Mutant
MGNA-B039 (yvqH::erm), available at the NBRP B. subtilis, Japan
BKE33120 (liaH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCTGATTCCTCCTAAT,  downstream forward: _UP4_TAAGCGGAACGGGGAAGGAT
BKK33120 (liaH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCTGATTCCTCCTAAT,  downstream forward: _UP4_TAAGCGGAACGGGGAAGGAT
References
Reviews
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Original Publications
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AE4BF12C368468C553EED7A696D5EFC63F56CA39

Page visits: 6439

Time of last update: 2025-04-13 17:01:11

Author of last update: Jstuelk