yetL

yetL
168

transcriptional repressor of yetM and yetL, induction in response to flavonoids

Locus
BSU_07220
Molecular weight
19.07 kDa
Isoelectric point
7.52
Protein length
167 aaSequenceBlast
Gene length
504 bpSequenceBlast
Function
regulation of yetM expression
Product
transcription repressor (MarR family)
Essential
no
Synonyms
yetL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1846 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
789,652 → 790,155
Phenotypes of a mutant
a point mutation in yetL may be involved in the acquisition of resistance to L-asparagine PubMed
The protein
Protein family
MarR family
Domains
HTH marR-type domain (aa 26-160) (according to UniProt)
Structure
7WZE (PDB) PubMed
O31541 (AlphaFold)
Effectors of protein activity
inducers: flavonoids of kaempferol, apigenin, and luteolin PubMed
Expression and Regulation
Operons
Genes
yetL
Description
PubMed
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yetL

2025-03-10 12:05:47

ghost

69

38bca86b039f722e93e0c9c46782a17bfab1ff28

7457BF78C5592BB9150DA918F550575FE459A8D4

Biological materials
Mutant
MGNA-B463 (yetL::erm), available at the NBRP B. subtilis, Japan
BKE07220 (ΔyetL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGCAATTAGCTCCCGTA,  downstream forward: _UP4_TAAAAAACCCGTCCGATCCG
BKK07220 (ΔyetL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGCAATTAGCTCCCGTA,  downstream forward: _UP4_TAAAAAACCCGTCCGATCCG
Expression vectors
pGP3934 (Cc-terminal Strep-tag, purification from E. coli, in pGP574), available in Jörg Stülke's lab
References
Reviews
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Original Publications
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BFAFC2CFA7F2FDA639B367C579E2A46242BA3DBD

Page visits: 3267

Time of last update: 2025-04-11 20:39:13

Author of last update: Dennis.wicke