yosP

yosP
168

similar to ribonucleoside-diphosphate reductase (beta subunit)

Locus
BSU_20040
Molecular weight
22.51 kDa
Isoelectric point
6.09
Protein length
598 aaSequenceBlast
Gene length
1798 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
yosP, nrdF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0208 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,159,981  2,161,778
The protein
Catalyzed reaction/ biological activity
[thioredoxin]-disulfide + 2'-deoxyribonucleoside 5'-diphosphate + H2O --> [thioredoxin]-dithiol + ribonucleoside 5'-diphosphate (according to UniProt)
Protein family
ribonucleoside diphosphate reductase small chain family (with NrdF, according to UniProt)
Structure
4DR0 (PDB) ( from Bacillus Subtilis 87% identity)
O30601 (AlphaFold)
Paralogous protein(s)
NrdF
Biological materials
Mutant
BKE20040 (yosP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCCTACATATACGCCAT,  downstream forward: _UP4_TTTACCGAGAAAGGATGTAT
BKK20040 (yosP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCCTACATATACGCCAT,  downstream forward: _UP4_TTTACCGAGAAAGGATGTAT
References
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Time of last update: 2025-04-10 12:38:04

Author of last update: Melvin.boenninger