btr

btr
168

transcriptional activator (AraC family), (AraC family DNA-binding domain fused to FeuA-like substrate-binding domain), regulation of the feuA-feuB-feuC-ybbA operon

Locus
BSU_01640
Molecular weight
60.59 kDa
Isoelectric point
6.43
Protein length
Gene length
Function
regulation of iron acquisition
Product
transcription activator (AraC family)
Essential
no
Synonyms
btr, ybbB, yzbC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2207 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
183,414 → 185,003
The protein
Catalyzed reaction/ biological activity
binding of a direct repeat in the feuA promoter region and transcription activation of the feuA-feuB-feuC-ybbA operon in the presence of bacillibactin or enterobactin PubMed
Protein family
Fe/B12 periplasmic-binding domain (aa 268-528) (according to UniProt)
enterobactin, bacillibactin (co-activators) PubMed
Structure
Effectors of protein activity
enterobactin, bacillibactin (co-activators) PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
expressed under conditions of iron starvation (Fur) PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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btr

2025-04-06 07:46:57

ghost

70

9430f6b2596e4102cac0bd3b6434172ab65dac98

8E607D8530622210BCE389315103A110307A88DD

Biological materials
Mutant
MGNA-B949 (ybbB::erm), available at the NBRP B. subtilis, Japan
BKE01640 (Δbtr::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CACGAGTAGACCACCTTTTC,  downstream forward: _UP4_TGATAAATCAGGAATTTGTC
BKK01640 (Δbtr::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CACGAGTAGACCACCTTTTC,  downstream forward: _UP4_TGATAAATCAGGAATTTGTC
References
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EB28A65CECE994DF2DF486DEACF40F2533703DB0

Page visits: 6050

Time of last update: 2025-04-06 07:28:16

Author of last update: Melvin.boenninger