rhgL

rhgL
168

two-component response regulator

Locus
BSU_06960
Molecular weight
40.50 kDa
Isoelectric point
6.95
Protein length
368 aaSequenceBlast
Gene length
1107 bpSequenceBlast
Function
unknown
Product
two-component response regulator
Essential
no
Synonyms
yesN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4753 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
760,452 → 761,558
The protein
Domains
Response regulatory domain (aa 3-120) (according to UniProt)
HTH araC/xylS-type domain (aa 259-361) (according to UniProt)
Structure
2JVJ (PDB) (Spo0F, the Response regulatory domain, 28% identity)
O31517 (AlphaFold)
Modification
phosphorylated on a Asp residue by RhgK
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
yesL-rhgK-rhgL
Description
PubMed
Regulation
induced by pectin PubMed
repressed by glucose (CcpA) PubMed
Regulatory mechanism
CcpA: repression, in ccpA regulon
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yesL->rhgL

2025-04-02 15:37:02

Jstuelk

94

0A0856680046F4A9A13DB901EA1DB74D20547B9B

13801837B9137F1D6F2BEE3267F800035E9436AB

Additional information
translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
Biological materials
Mutant
MGNA-A946 (yesN::erm), available at the NBRP B. subtilis, Japan
BKE06960 (ΔrhgL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCAGCCAGCAGTATTTTAT,  downstream forward: _UP4_TAGCCATCTCTGTTTTTTTG
BKK06960 (ΔrhgL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCAGCCAGCAGTATTTTAT,  downstream forward: _UP4_TAGCCATCTCTGTTTTTTTG
References
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F09661C8A483D0FC796204102021104A4373F895

Page visits: 2410

Time of last update: 2025-04-06 02:41:10

Author of last update: Jstuelk