hepS

hepS
168

heptaprenyl diphosphate synthase component I

Locus
BSU_22760
Molecular weight
28.97 kDa
Isoelectric point
6.27
Protein length
Gene length
Function
menaquinone biosynthesis
Product
heptaprenyl diphosphate synthase component I (together with HepT)
Essential
no
E.C.
2.5.1.30
Synonyms
hepS, gerCA, hepA

Genomic Context

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,383,615 → 2,384,370
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth PubMed
essential PubMed, non-essential according to PubMed
The protein
Catalyzed reaction/ biological activity
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate --> all-trans-heptaprenyl diphosphate + 4 diphosphate (according to UniProt)
Structure
Expression and Regulation
Operons
Description
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hepSndk

2025-01-14 13:48:25

Jstuelk

135

4994bd02adb7701a42b6eebb6e0352c9f8a44e38

8B6317CB1523DAD0B462E932EA20388911064C0F

Biological materials
Mutant
BKE22760 (ΔhepS::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAAAAATATCACCCTTGTCC,  downstream forward: _UP4_TAAACCATTATGCAGGACTC
BKK22760 (ΔhepS::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAAAAATATCACCCTTGTCC,  downstream forward: _UP4_TAAACCATTATGCAGGACTC
References
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C45A5935559F0DAAD70F808725AF730BC18A2B0A

Page visits: 3434

Time of last update: 2025-01-19 00:35:09

Author of last update: Christoph.elfmann