Difference between revisions of "RecU"

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(Original publications)
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<pubmed> 22933559 9442895</pubmed>
 
<pubmed> 22933559 9442895</pubmed>
 
== Original publications ==
 
== Original publications ==
<pubmed>9642195,16024744,15317759,11810266,19730681 , 19422832 7814321 18179421 16154091 21600217 18684995 16020779 24770420 </pubmed>
+
<pubmed>9642195,16024744,15317759,11810266,19730681 , 19422832 7814321 18179421 16154091 21600217 18684995 16020779 24770420 24792171 </pubmed>
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==RecU in other organisms==
 
==RecU in other organisms==
 
<pubmed>23356868 </pubmed>
 
<pubmed>23356868 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 07:34, 6 May 2014

  • Description: Holliday junction resolvase, DNA repair, homologous recombination and chromosome segregation; recognizes, distorts, and cleaves four-stranded recombination intermediates and modulates RecA activities, equivalent to E. coli RecU

Gene name recU
Synonyms recG, prfA, yppB, jopB
Essential no
Product Holliday junction resolvase
Function DNA repair/ recombination and chromosome segregation
Gene expression levels in SubtiExpress: recU
Interactions involving this protein in SubtInteract: RecU
MW, pI 23 kDa, 9.511
Gene length, protein length 618 bp, 206 aa
Immediate neighbours yppC, ponA
Sequences Protein DNA DNA_with_flanks
Genetic context
RecU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RecU expression.png
















Categories containing this gene/protein

DNA repair/ recombination, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU22310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds Holliday junctions with high affinity PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:
    • RecU-mediated Holliday junction resolution is stimulated by RuvB-ATP PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications


RecU in other organisms

Ana R Pereira, Patricia Reed, Helena Veiga, Mariana G Pinho
The Holliday junction resolvase RecU is required for chromosome segregation and DNA damage repair in Staphylococcus aureus.
BMC Microbiol: 2013, 13;18
[PubMed:23356868] [WorldCat.org] [DOI] (I e)