gerBA
168

nutrient receptor, germination response to the combination of glucose, fructose, and KCl

Locus

BSU_35800

Molecular weight

53.62 kDa

Isoelectric point

7.3

Protein length

483 aaSequenceBlast

Gene length

1452 bpSequenceBlast

Function

germination response to the combination of glucose, fructose, and KCl

Product

part of the putative nutrient-gated GerBA-GerBB-GerBC ion channel

Essential

Synonyms

gerBA

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5901 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

3,688,812 3,690,263

The protein

Catalyzed reaction/ biological activity

the GerBA-GerBB-GerBC ion channel likely releases ions from the spore core in response to asparagine, glucose, fructose and K⁺ to trigger Germination, this requires the gerK locus PubMed

Protein family

GerABKA family (according to UniProt)

Structure

6O59 (PDB) (from B. megaterium, corresponds to aa 7 ... 264, 36.5% identity) PubMed

P39569 (AlphaFold)

Paralogous protein(s)

YfkQ, YndD, GerKA, GerAA

Localization

spore inner membrane PubMed

Expression and Regulation

Operons

Genes

gerBA-gerBB-gerBC

Description

PubMed

Regulation

expressed late during sporulation in the forespore (SigG) PubMed

Sigma factors

SigG: sigma factor, PubMed, in sigG regulon

Additional information

700 molecules are present per spore PubMed

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Biological materials

Mutant

BKE35800 (gerBA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAGTTTCTCTCCTTCTTA, downstream forward: _UP4_AACATCAGACAAAGGTGATG

BKK35800 (gerBA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAGTTTCTCTCCTTCTTA, downstream forward: _UP4_AACATCAGACAAAGGTGATG

References

Reviews

Original Publications

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Time of last update: 2025-04-11 00:17:28

Author of last update: Jstuelk

gerBA 168

gerBA
168