hemZ

hemZ
168

coproporphyrinogen III oxidase

Locus
BSU_09840
Molecular weight
57.00 kDa
Isoelectric point
5.899
Protein length
501 aaSequenceBlast
Gene length
1506 bpSequenceBlast
Function
heme biosynthesis
Product
coproporphyrinogen III oxidase
Essential
no
Synonyms
hemZ, yhaW, yhaV
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0635 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,057,680  1,059,185
The protein
Protein family
anaerobic coproporphyrinogen-III oxidase family (with HemN, according to UniProt)
Cofactors
Fe-S cluster PubMed
Structure
Q796V8 (AlphaFold)
Paralogous protein(s)
HemN
Expression and Regulation
Operons
Genes
hemZ
Description
PubMed
Regulation
induced under anaerobic conditions during growth in the presence of nitrate (no induction in the absence of terminal electron acceptor) (Fnr, ResD, ArfM) PubMed
Regulatory mechanism
Rex: repression, in rex regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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hemZ

2025-03-09 11:14:54

ghost

70

fd1aa3303fdb93cbd553351d820d6443f298b86b

DA3C9D6F41198957983C9A52BFA28A451759CEFC

Biological materials
Mutant
MGNA-B497 (yhaV::erm), available at the NBRP B. subtilis, Japan
BKE09840 (hemZ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTTCATCACCTAATTTA,  downstream forward: _UP4_CACTGATTACAGTGCTGCTT
BKK09840 (hemZ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTTCATCACCTAATTTA,  downstream forward: _UP4_CACTGATTACAGTGCTGCTT
References
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Page visits: 2927

Time of last update: 2025-04-23 00:20:26

Author of last update: Melvin.boenninger