fadF

fadF
168

similar to iron-sulphur-binding reductase

Locus
BSU_37180
Molecular weight
79.00 kDa
Isoelectric point
6.53
Protein length
705 aaSequenceBlast
Gene length
2118 bpSequenceBlast
Function
fatty acid degradation
Product
unknown
Essential
no
Synonyms
fadF, ywjF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0247 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,814,382 → 3,816,499
The protein
Domains
2 4Fe-4S ferredoxin-type domains (aa 268-298, aa 360-391) (according to UniProt)
Cofactors
2 4Fe-4S clusters PubMed
Structure
P45866 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
fadF-acdA-rpoE
Description
PubMed
Regulation
repressed in the absence of long-chain fatty acids (FadR) PubMed
Regulatory mechanism
FadR: repression, PubMed, in fadR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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fadF→rpoE

2025-04-04 22:46:51

Jstuelk

137

404be419ef45bd05929352ef6ba5dc0e434ec1c3

9C9A5D2281D0C2A74A807FF5D3F4169BC992CAFF

Biological materials
Mutant
MGNA-A555 (ywjF::erm), available at the NBRP B. subtilis, Japan
BKE37180 (''fadF::erm'', available in the BGSC, in Fabian Commichau's, and in Jörg Stülke's lab) PubMed
BKE37180 (ΔfadF::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCCAATTCCCCCTTTTT,  downstream forward: _UP4_GATCTGAAAATGGGGGAGAA
BKK37180 (ΔfadF::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCCAATTCCCCCTTTTT,  downstream forward: _UP4_GATCTGAAAATGGGGGAGAA
References
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DEE0DA15EE9EA27BA8C332204E40D336324A111C

Page visits: 4432

Time of last update: 2025-04-09 20:58:03

Author of last update: Melvin.boenninger