nadF

nadF
168

NAD kinase

Locus
BSU_11610
Molecular weight
29.86 kDa
Isoelectric point
5.99
Protein length
266 aaSequenceBlast
Gene length
801 bpSequenceBlast
Function
generation of NADP from NAD
Product
inorganic polyphosphate/ATP-NAD kinase
Essential
yes
E.C.
2.7.1.23
Synonyms
nadF, yjbN, ppnK, ppnKA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG0061 (Galperin et al., 2021)

Gene
Coordinates
1,237,660  1,238,460
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
ATP + NAD+ --> ADP + H+ + NADP+ (according to UniProt)
Protein family
NAD kinase family (with YtdI, according to UniProt)
Structure
2I1W (PDB) (from Listeria monocytogenes, 60% identity) PubMed
O31612 (AlphaFold)
Effectors of protein activity
allosterically activated by quinolinic acid
Paralogous protein(s)
YtdI
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
yjbL-sasB-nadF-yjbO
Description
PubMed
Regulation
expressed during exponential growth
Open in new tab

yjbL→yjbO

2025-04-03 22:19:01

Jstuelk

101

c5edd61e714281007d4d9ec99a1efa0cfef63f09

83E46551CBC32AB07130281546FE3D422612C2C3

Biological materials
Mutant
MGNA-B160 (yjbN::erm), available at the NBRP B. subtilis, Japan
1A825 ( nadF::erm), PubMed, available at BGSC
References
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2A2640A0501ECEA44A3C0C4842FAC053FB422A1F

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Time of last update: 2025-04-07 05:00:56

Author of last update: Melvin.boenninger