exuR

exuR
168

repression of the hexuronate utilization operon (uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA)

Locus
BSU_12370
Molecular weight
37.22 kDa
Isoelectric point
5.85
Protein length
333 aaSequenceBlast
Gene length
1002 bpSequenceBlast
Function
regulation of hexuronate utilization
Product
transcriptional repressor (LacI family)
Essential
no
Synonyms
exuR, yjmH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,308,802  1,309,803
The protein
Protein family
LacI family
Domains
HTH lacI-type domain (aa 2-56) (according to UniProt)
Structure
2HSG (PDB) (CcpA, 32% identity) PubMed
Q9JMQ1 (AlphaFold)
Effectors of protein activity
galacturonate acts as the molecular inducer PubMed
Expression and Regulation
Operons
Genes
yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
Description
PubMed
Regulation
induced by galacturonate (ExuR) PubMed
Regulatory mechanism
ExuR: repression, in the absence of inducer, in exuR regulon
CcpA: repression, PubMed PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigE: sigma factor, PubMed, in sigE regulon
Open in new tab

yjmC→uxaA

2025-04-08 12:07:13

ghost

93

e9b60dda83535baf9252c89c7130d2fdeb844e6f

417675688A3DB0A933113CA632D3321516D969A2

Genes
uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
Description
PubMed
Regulation
induced by galacturonate (ExuR) PubMed
Regulatory mechanism
ExuR: repression, in the absence of inducer, in exuR regulon
CcpA: repression, PubMed PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

uxaC→uxaA

2025-04-03 12:22:40

ghost

96

0325999ea185bfaaf2dea87e1701479c52256033

A15F6E93B04DC8C4B59B7976DAC34CE9AC0B8E51

Biological materials
Mutant
MGNA-A372 (yjmH::erm), available at the NBRP B. subtilis, Japan
BKE12370 (exuR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTAATTCCCTTCCTTAT,  downstream forward: _UP4_TGATGTCCCGTTTTTCAGCG
BKK12370 (exuR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTAATTCCCTTCCTTAT,  downstream forward: _UP4_TGATGTCCCGTTTTTCAGCG
References
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69B143987DCF73B5D080E3FD87A6CA2940E07DA8

Page visits: 5528

Time of last update: 2025-04-12 11:25:19

Author of last update: Melvin.boenninger