cmk
168
cytidylate kinase (CMP, dCMP)
Locus
BSU_22890
Molecular weight
24.95 kDa
Isoelectric point
5
Function
synthesis of CTP and dCTP
Product
cytidylate kinase (CMP, dCMP)
Essential
yes
E.C.
2.7.4.14
Synonyms
cmk, jofC, ypfC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0283 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
The protein
Catalyzed reaction/ biological activity
ATP + CMP --> ADP + CDP (according to UniProt)
ATP + dCMP --> ADP + dCDP (according to UniProt)
Protein family
cytidylate kinase family (single member, according to UniProt)
Structure
1CKE (PDB) (from Escherichia coli, 38% identity, 54% similarity) PubMed
Expression and Regulation
Operons
References
Structural and catalytic properties of CMP kinase from Bacillus subtilis: a comparative analysis with the homologous enzyme from Escherichia coli.
Archives of biochemistry and biophysics. 1997 Apr 01; 340(1):144-53. . PMID:9126287
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Time of last update: 2025-04-10 18:28:44
Author of last update: Melvin.boenninger