yxeM

yxeM
168

putative S-(2-succino)cysteine ABC transporter (binding protein)

Locus
BSU_39500
Molecular weight
29.16 kDa
Isoelectric point
9.09
Protein length
264 aaSequenceBlast
Gene length
795 bpSequenceBlast
Function
uptake and utilization of S-(2-succino)cysteine
Product
putative S-(2-succino)cysteine ABC transporter (binding protein)
Essential
no
Synonyms
yxeM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0834 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,059,488 → 4,060,282
The protein
Protein family
bacterial solute-binding protein 3 family (according to UniProt)
Structure
4ZV1 (PDB) (synthetic, 38% identity) PubMed
P54952 (AlphaFold)
Localization
associated to the membrane (via YxeN) PubMed
Expression and Regulation
Operons
Genes
yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ
Description
PubMed
Regulation
repressed in the presence of cysteine (CymR) PubMed
Regulatory mechanism
CymR: repression, PubMed, in cymR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed
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yxeK→yxeQ

2025-03-31 02:55:29

Bzhu

101

26e7d8a77b7f64e210508bce49d61eed26cdd5aa

11F447FD5833B59A1639842D70685F9A6B369EAF

Biological materials
Mutant
MGNA-B782 (yxeM::erm), available at the NBRP B. subtilis, Japan
1A950 ( yxeM::cat), PubMed, available at BGSC
BKE39500 (ΔyxeM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGATTTTCCCGCCTTT,  downstream forward: _UP4_TAAGAAACGGCGGTGACTCA
BKK39500 (ΔyxeM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGATTTTCCCGCCTTT,  downstream forward: _UP4_TAAGAAACGGCGGTGACTCA
References
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D96EEDABB73AC66E6AB772431819E7C767DC8B9A

Page visits: 5073

Time of last update: 2025-04-11 18:23:09

Author of last update: Jstuelk