dppE

dppE
168

dipeptide ABC transporter (dipeptide-binding protein)

Locus
BSU_12960
Molecular weight
62.41 kDa
Isoelectric point
5.52
Protein length
549 aaSequenceBlast
Gene length
1650 bpSequenceBlast
Function
uptake of dipeptides
Product
dipeptide ABC transporter (dipeptide-binding protein)
Essential
no
Synonyms
dppE, dciAE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4166 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,364,151  1,365,800
The protein
Protein family
bacterial solute-binding protein 5 family (according to UniProt)
Structure
8AZB (PDB) PubMed
4FAJ (PDB) (from Enterococcus faecalis, 33% identity) PubMed
P26906 (AlphaFold)
Paralogous protein(s)
OppA
Localization
attached to the cell membrane (via DppB-DppC) PubMed
Expression and Regulation
Operons
Genes
dppA-dppB-dppC-dppD-dppE
Description
PubMed
Regulation
repressed by glucose (2.9-fold) PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

dppA→dppE

2025-04-06 00:53:48

Jstuelk

126

09ee4083370400f9df0298a2b88ab5c0bbf1df43

5AB4A35A00613327500FE4CC530C2BFA97A6C07B

Genes
dppA-dppB-dppC-dppD-dppE-ykfA-ykfB-ykfC-ykfD
Description
PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
Open in new tab

dppA->ykfD

2025-03-27 02:00:36

Bzhu

140

9978370314fc05087eca13c4f3ce94e92ce93ff2

E2A0CC9BE866DBD9F0E3A5F48EE05465C14EFD9D

Biological materials
Mutant
GP1110 (spc), available in Jörg Stülke's lab
1A737 ( dppE::kan), PubMed, available at BGSC
BKE12960 (dppE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTCTTCCCCCTTTTCA,  downstream forward: _UP4_TGATGGAGGCGATTGAGGAA
BKK12960 (dppE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTCTTCCCCCTTTTCA,  downstream forward: _UP4_TGATGGAGGCGATTGAGGAA
References
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853C570CFB9382449A20BE77B44B4FE44972AA59

Page visits: 6386

Time of last update: 2025-04-06 18:38:07

Author of last update: Jstuelk