sdhB

sdhB
168

succinate dehydrogenase (iron-sulfur protein)

Locus
BSU_28430
Molecular weight
28.27 kDa
Isoelectric point
7.99
Protein length
253 aaSequenceBlast
Gene length
762 bpSequenceBlast
Function
TCA cycle
Product
succinate dehydrogenase (iron-sulfur protein)
Essential
no
Synonyms
sdhB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0479 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,905,571  2,906,332
The protein
Catalyzed reaction/ biological activity
quinone + succinate --> quinol + fumarate (according to UniProt)
Protein family
succinate dehydrogenase/fumarate reductase iron-sulfur protein family (single member, according to UniProt)
Domains
4Fe-4S ferredoxin-type domain (aa 146-174) (according to UniProt)
Cofactors
Fe-S cluster PubMed
Structure
1NEK (PDB) (E. coli) PubMed
P08066 (AlphaFold)
Effectors of protein activity
Inhibited by 2-(n-Heptyl)-4-hydroxy-quinoline N-oxide PubMed
Activated by Cytochrome b558 PubMed
Localization
attached to the membrane PubMed
Expression and Regulation
Operons
Genes
sdhC-sdhA-sdhB
Description
PubMed
Regulation
constitutive
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

sdhC→sdhB

2025-03-24 13:01:55

ghost

85

6e4216337509de45d76033b51f5046e391052666

7F08B53F36BD96778ADC5652AD8BF65AF07550E2

Other regulations
FsrA: translation inhibition, PubMed
Biological materials
Mutant
GP792 ∆(sdhC-sdhA-sdhB)::phleo, available in Jörg Stülke's lab
GP2342 ∆(sdhC-sdhA-sdhB)::kan, Cre-recombinase is integrated in sacA, available in Jörg Stülke's lab
GP2343 ∆(sdhC-sdhA-sdhB)::lox72, Cre-recombinase is integrated in sacA, available in Jörg Stülke's lab
References
Reviews
Loading
Original Publications
Loading

901F90AFC94CC7140709845333416106D043269D

Page visits: 3749

Time of last update: 2025-04-06 03:32:16

Author of last update: Jstuelk