glpD

glpD
168

glycerol-3-phosphate dehydrogenase (menaquinone 7)

Locus
BSU_09300
Molecular weight
62.36 kDa
Isoelectric point
8
Protein length
555 aaSequenceBlast
Gene length
1668 bpSequenceBlast
Function
glycerol utilization
Product
glycerol-3-phosphate dehydrogenase (menaquinone 7)
Essential
no
E.C.
1.1.5.3
Synonyms
glpD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0578 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,004,975 → 1,006,642
The protein
Catalyzed reaction/ biological activity
quinone + sn-glycerol 3-phosphate --> quinol + dihydroxyacetone phosphate (according to UniProt)
Protein family
FAD-dependent glycerol-3-phosphate dehydrogenase family (single member, according to UniProt)
Cofactors
FAD (according to UniProt)
Structure
3DA1 (PDB) (from Bacillus halodurans, 57% identity, 72% similarity)
P18158 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
glpD
Description
PubMed
Regulation
induced by glycerol (GlpP) PubMed
Regulatory mechanism
CcpA: repression, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
GlpP: antitermination, at a RNA switch PubMed, in glpP regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

glpD

2025-03-16 17:55:28

ghost

96

0de22157bc68a9b7b0579b06ff64224619cd7d50

442B20CD12F388D4E6BC03E9B61A5A1D90D3B2E2

Biological materials
Mutant
QB5347 (cat), available in the Stülke lab
BKE09300 (ΔglpD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTACGTTTCCTCCTTGTT,  downstream forward: _UP4_TAAATCATAACGGGCTGTCT
BKK09300 (ΔglpD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTACGTTTCCTCCTTGTT,  downstream forward: _UP4_TAAATCATAACGGGCTGTCT
References
Loading

BB42AE1AAFA3229649A8E210C1F6D7B61AF38BA1

Page visits: 5718

Time of last update: 2025-04-06 04:21:52

Author of last update: Jstuelk