yktC

yktC
168

inositol monophosphatase and 5'-nucleotidase with preference for GMP and IMP

Locus
BSU_14670
Molecular weight
29.61 kDa
Isoelectric point
5.09
Protein length
Gene length
Function
unknown
Product
nucleotidase
Essential
no
E.C.
3.1.3.25
Synonyms
yktC, suhB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0483 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,537,441  1,538,238
Phenotypes of a mutant
sensitive to diamide stress PubMed
The protein
Catalyzed reaction/ biological activity
myo-inositol phosphate + H2O --> myo-inositol + phosphate (according to UniProt)
Protein family
inositol monophosphatase superfamily (single member, according to UniProt)
Structure
5I3S (PDB) (from Staphylococcus aureus, 51% identity)
Expression and Regulation
Operons
Genes
Description
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
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yktC->ykzC

2025-01-12 04:57:05

Bzhu

48

133db3115c3287426f3d0993352a6cd7e2ce853b

51CBFA564E58E1077A5A313A4FB9C32F92524956

Biological materials
Mutant
MGNA-A908 (yktC::erm), available at the NBRP B. subtilis, Japan
BKE14670 (yktC::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTCGTTCGTACCTCTCTT,  downstream forward: _UP4_TAGGCCATTTGAGCAGGATG
BKK14670 (yktC::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTCGTTCGTACCTCTCTT,  downstream forward: _UP4_TAGGCCATTTGAGCAGGATG
References
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AD151804FC145854DB6BAA12CD52758FB1C3882F

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Time of last update: 2025-01-18 05:33:10

Author of last update: Melvin.boenninger