YvrHb

• Description: two-component response regulator
  
  

Gene name	yvrHb
Synonyms	yvrH
Essential	no
Product	two-component response regulator
Function	regulation cell surface maintenance
Gene expression levels in SubtiExpress: yvrHb
Interactions involving this protein in SubtInteract: YvrHB
MW, pI	27 kDa, 5.235
Gene length, protein length	711 bp, 237 aa
Immediate neighbours	yvrG, yvrHa
Gene sequence (+200bp)	Protein sequence
Genetic context
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, phosphoproteins

The gene

Basic information

• Locus tag: BSU33221

Phenotypes of a mutant

unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed

Database entries

• BsubCyc: BSU33221

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription activator PubMed

• Protein family: OmpR family

• Paralogous protein(s):

The YvrHb regulon

subject to positive control: dltA-dltB-dltC-dltD-dltE, sigX-rsiX, sunA, sunT-bdbA-yolJ-bdbB, wapA-yxxG, wprA, yvrI-yvrHa PubMed

subject to negative control: lytA-lytB-lytC PubMed

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation (Asp) by YvrG PubMed

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions:
  • YvrG-YvrHb PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU33221

• Structure:

• Swiss prot entry: P94504

• KEGG entry: [1]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yvrHb PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 267 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 459 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: