mnmM
168
SAM-dependent class I 5-aminomethyl-2-thiouridine methyltransferase
Locus
BSU_30490
Molecular weight
21.14 kDa
Isoelectric point
5.56
Function
tRNA modification at U34
Product
SAM-dependent class I 5-aminomethyl-2-thiouridine methyltransferase
Essential
no
Synonyms
ytqB, MnmM
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0275 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,120,964 → 3,121,548
The protein
Catalyzed reaction/ biological activity
modification of tRNA at U34, conversion of 5-aminomethyl-(2-thio)uridine to 5-methylaminomethyl-(2-thio)uridine PubMed
Protein family
Methyltransferase superfamily (according to UniProt)
SAM PubMed
Structure
4PON (PDB), apoenzyme PubMed
4POO (PDB), complex with SAM PubMed
8H1B (PDB), MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-A165 (ytqB::erm), available at the NBRP B. subtilis, Japan
References
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Time of last update: 2025-01-25 18:42:31
Author of last update: Jstuelk