corA

corA
168

general stress protein, similar to magnesium transporter

Locus
BSU_24740
Molecular weight
37.55 kDa
Isoelectric point
9.54
Protein length
317 aaSequenceBlast
Gene length
954 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
corA, yqhC, yqxL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0598 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,560,489 → 2,561,442
The protein
Catalyzed reaction/ biological activity
there is no indication for an implication of CorA in Mg2 uptake (based on mutant phenotypes, failure to complement mutants defective in Mg2 uptake) PubMed
Protein family
CorA metal ion transporter (MIT) (TC 1.A.35) family (together with YfjQ) (according to UniProt)
Structure
5JTG (PDB) (from Themotoga maritima, C-terminal domain, aa 122-297, 28% identity)
P40948 (AlphaFold)
Localization
inner spore membrane PubMed
Expression and Regulation
Operons
Genes
corA
Description
PubMed
Regulation
induced by stress (SigB) PubMed
Regulatory mechanism
LexA: repression, PubMed, in lexA regulon
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
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corA

2025-03-16 16:15:04

ghost

62

dad9929632067584005f4f6538b96b0d2c66005a

C63DF20DE434F8245D920A449446202051477C4A

Biological materials
Mutant
MGNA-C473 (yqxL::erm), available at the NBRP B. subtilis, Japan
BKE24740 (ΔcorA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT
BKK24740 (ΔcorA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCAAGCTCCTCCAAAC,  downstream forward: _UP4_TAGGATGTTTCATATTTTGT
References
Reviews
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Original Publications
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F0CACEFB53F4BC38DF77A38C4D78BA3DBE96E21A

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Time of last update: 2025-04-10 05:21:19

Author of last update: Jstuelk