czcO

czcO
168

similar to flavin-containing monooxygenase, facilitates cation export via CzcD

Locus
BSU_26640
Molecular weight
38.91 kDa
Isoelectric point
9.83
Protein length
345 aaSequenceBlast
Gene length
1038 bpSequenceBlast
Function
resistance to toxic metal ions
Product
unknown
Essential
no
Synonyms
czcO, trkA, yrdP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2072 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,722,767  2,723,804
The protein
Structure
4USQ (PDB) (from Cellvibrio sp., 23% identity) PubMed
O07085 (AlphaFold)
Expression and Regulation
Operons
Genes
czcD-czcO
Description
PubMed
Regulation
induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) (CzrA) PubMed
Regulatory mechanism
CzrA: repression, PubMed, in czrA regulon
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czcD→czcO

2025-04-03 06:29:37

ghost

73

430ab856fd55b6eef5935b0d08aeb7c4ec8a07ad

CA86623CDC188C345091326FF4E65FA2529C0CB9

Biological materials
Mutant
BKE26640 (czcO::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATTATCACCCCGCCAAT,  downstream forward: _UP4_TAAACGAAGCAGAGCAGTAA
BKK26640 (czcO::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATTATCACCCCGCCAAT,  downstream forward: _UP4_TAAACGAAGCAGAGCAGTAA
References
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Page visits: 2611

Time of last update: 2025-04-10 11:04:16

Author of last update: Jstuelk