Difference between revisions of "NadD"
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|style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640 nadD] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=NadD NadD]''' | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]'' | ||
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25640 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:nadD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | |||
<br/><br/> | <br/><br/> | ||
+ | |||
+ | = [[Categories]] containing this gene/protein = | ||
+ | {{SubtiWiki category|[[biosynthesis of cofactors]]}}, | ||
+ | {{SubtiWiki category|[[essential genes]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
+ | |||
=The gene= | =The gene= | ||
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=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Locus tag:''' BSU25640 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Additional information=== | === Additional information=== | ||
+ | |||
+ | |||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD<sup>+</sup> (according to Swiss-Prot) |
* '''Protein family:''' nadD family (according to Swiss-Prot) | * '''Protein family:''' nadD family (according to Swiss-Prot) | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
− | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ] | ||
− | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P54455 P54455] |
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU25640] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.18 2.7.7.18] | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.18 2.7.7.18] | ||
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* '''Operon:''' | * '''Operon:''' | ||
+ | |||
+ | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 nadD] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
+ | <pubmed> 11704676 </pubmed> | ||
− | + | [[Category:Protein-coding genes]] |
Latest revision as of 11:48, 8 April 2014
- Description: nicotinamide-nucleotide adenylyltransferase
Gene name | nadD |
Synonyms | yqeJ |
Essential | yes PubMed |
Product | nicotinamide-nucleotide adenylyltransferase |
Function | NAD biosynthesis |
Gene expression levels in SubtiExpress: nadD | |
Metabolic function and regulation of this protein in SubtiPathways: NadD | |
MW, pI | 22 kDa, 5.123 |
Gene length, protein length | 567 bp, 189 aa |
Immediate neighbours | yqeK, yqeI |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25640
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU25640
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+ (according to Swiss-Prot)
- Protein family: nadD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU25640
- Structure: 1KAQ
- UniProt: P54455
- KEGG entry: [2]
- E.C. number: 2.7.7.18
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References