Difference between revisions of "NadD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640 nadD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=NadD NadD]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.123   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqeK]]'', ''[[yqeI]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14506&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25640 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqeJ_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:nadD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25640]]
 
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__TOC__
 
__TOC__
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=== Database entries ===
 
=== Database entries ===
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* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
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=== Database entries ===
 
=== Database entries ===
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* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25640&redirect=T BSU25640]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1KAQ 1KAQ]
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* '''Operon:'''  
 
* '''Operon:'''  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadD_2643765_2644334_-1 nadD] {{PubMed|22383849}}
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
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* '''Additional information:'''  
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* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Latest revision as of 11:48, 8 April 2014

  • Description: nicotinamide-nucleotide adenylyltransferase

Gene name nadD
Synonyms yqeJ
Essential yes PubMed
Product nicotinamide-nucleotide adenylyltransferase
Function NAD biosynthesis
Gene expression levels in SubtiExpress: nadD
Metabolic function and regulation of this protein in SubtiPathways:
NadD
MW, pI 22 kDa, 5.123
Gene length, protein length 567 bp, 189 aa
Immediate neighbours yqeK, yqeI
Sequences Protein DNA DNA_with_flanks
Genetic context
YqeJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NadD expression.png
























Categories containing this gene/protein

biosynthesis of cofactors, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25640

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+ (according to Swiss-Prot)
  • Protein family: nadD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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