resB
168

part of haem translocase, required for cytochrome c synthesis

Locus

BSU_23140

Molecular weight

61.59 kDa

Isoelectric point

9.47

Protein length

542 aaSequenceBlast

Gene length

1629 bpSequenceBlast

Function

cytochrome c biogenesis

Product

part of the ResB-ResC haem translocase

Essential

Synonyms

resB, ypxB

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

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Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1333 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

2,419,179 2,420,807

Phenotypes of a mutant

essential PubMed, non-essential according to PubMed

The protein

Catalyzed reaction/ biological activity

haem-binding protein, translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane PubMed

Structure

P35161 (AlphaFold)

Localization

cell membrane ResB-ResC PubMed

Expression and Regulation

Operons

Genes

rluB-resA-resB-resC-resD-resE

Description

PubMed

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Genes

resA-resB-resC-resD-resE

Description

PubMed

Regulation

expressed under anaerobic conditions (ResD) PubMed

Regulatory mechanism

ResD: activation, PubMed, in resD regulon

PhoP: activation, PubMed, in phoP regulon

CcpA: repression, PubMed, in ccpA regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

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Biological materials

Mutant

BKE23140 (resB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCCGCATTCACATTTGACTT, downstream forward: _UP4_AAATAGGCGAAAAGGGAGTG

BKK23140 (resB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCCGCATTCACATTTGACTT, downstream forward: _UP4_AAATAGGCGAAAAGGGAGTG

References

Reviews

Original Publications

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Time of last update: 2025-04-10 23:08:26

Author of last update: Jstuelk

resB 168

resB
168