iolF
168

D-chiro-inositol transport protein

Locus

BSU_39710

Molecular weight

47.03 kDa

Isoelectric point

9.47

Protein length

439 aaSequenceBlast

Gene length

1317 bpSequenceBlast

Function

D-chiro-inositol uptake

Product

D-chiro-inositol transport protein

Essential

Synonyms

iolF, yxdF

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

4,076,842 → 4,078,158

The protein

Catalyzed reaction/ biological activity

uptake of D-chiro-inositol PubMed

Protein family

major facilitator superfamily (according to UniProt)

Sugar transporter (TC 2.A.1.1) family (according to UniProt)

Structure

4LDS (PDB) (from S. epidermidis, 26% identity) PubMed

P42417 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes

iolA-iolB-iolC-iolD-iolE-iolF-iolG-iolH-iolI-iolJ

Description

PubMed

Regulation

induced by inositol (IolR) PubMed

Regulatory mechanism

IolR: repression, PubMed, in iolR regulon

CcpA: repression, PubMed, in ccpA regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

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Biological materials

Mutant

MGNA-B697 (iolF::erm), available at the NBRP B. subtilis, Japan

BKE39710 (ΔiolF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTTCATTCCCCATTA, downstream forward: _UP4_TAACCAACAGAAGGAGTGGC

BKK39710 (ΔiolF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTTCATTCCCCATTA, downstream forward: _UP4_TAACCAACAGAAGGAGTGGC

Labs working on this gene/protein

Yasutaro Fujita, University of Fukuyama, Japan

[[Ken-ichi Yoshida]], Kobe University, Japan

References

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Time of last update: 2025-04-13 17:40:35

Author of last update: Jstuelk

iolF 168

iolF
168